3,4-Dihydroxybenzylamine hydrobromide

Base Information

• Chemical Name: 3,4-Dihydroxybenzylamine hydrobromide
• CAS No.: 16290-26-9
• Molecular Formula: C7H9 N O2 . Br H
• Molecular Weight: 220.066
• Hs Code.: 29222900
• European Community (EC) Number: 240-382-8
• ChEMBL ID: CHEMBL1982505
• DSSTox Substance ID: DTXSID10936760
• NSC Number: 263475
• Mol file: 16290-26-9.mol

Synonyms:3,4-dihydroxybenzylamine;3,4-dihydroxybenzylamine hydrobromide;3,4-dihydroxybenzylamine hydrochloride

Chemical Property of 3,4-Dihydroxybenzylamine hydrobromide

Chemical Property:

• Appearance/Colour: light beige crystalline powder
• Vapor Pressure: 1.32E-05mmHg at 25°C
• Melting Point: 184-186 °C(lit.)
• Boiling Point: 333.4°Cat760mmHg
• Flash Point: 155.5°C
• PSA: 66.48000
• Density: 1.309g/cm³
• LogP: 2.21490
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive.: Hygroscopic
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 218.98949
• Heavy Atom Count: 11
• Complexity: 108

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-(Aminomethyl)benzene-1,2-diolHydrobromide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=C(C=C1CN)O)O.Br
• Uses: 4-(Aminomethyl)benzene-1,2-diol hydrobromide is a useful reactant for the synthesis of capsaicin soft drugs. which are used to target the transient receptor potential vanilloid 1 channel (TRPV1).

Technology Process of 3,4-Dihydroxybenzylamine hydrobromide

There total 1 articles about 3,4-Dihydroxybenzylamine hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3,4-dihydroxybenzylamine hydrobromide (16290-26-9)

Guidance literature:

3-Methoxy-4-hydroxybenzylamin, wss. HBr;

Reference yield: 91.0%

3,4-dihydroxybenzylamine hydrobromide (16290-26-9) + 4-Methoxymethylen-1,2,3,4-tetrahydroisochinolin-1,3-dion (78363-88-9) → 4-[(3,4-dihydroxybenzylamino)methylene]-4H-isoquinoline-1,3-dione (943748-55-8)

Guidance literature:

In N,N-dimethyl-formamide; at 115 ℃; for 1.5h;

DOI:10.1021/jm801026e

Reference yield: 84.0%

Nα-(9-fluorenylmethoxycarbonyl)-Nδ-methyltrityl-L-glutamine + 3,4-dihydroxybenzylamine hydrobromide (16290-26-9) → N-[Nα-(9-fluorenylmethoxycarbonyl)-Nδ-methyltrityl-L-glutaminyl]-3,4-dihydroxybenzylamine

Guidance literature:

With acetic acid; In ethyl acetate;

Downstream raw materials:

1-(3,4-dihydroxybenzyl)-4-thiopyridone

Thioacetic acid S-[2-(3,4-dihydroxy-benzylcarbamoyl)-3-phenyl-propyl] ester

3',4'-dihydroxybenzylamino-carbamic acid p-(bis-2-chloroethylamino)phenyl ester

2-benzyl-3-mercaptopropionic acid 3,4-dihydroxybenzylamide