2-ETHYL-6-METHYLPHENYL ISOTHIOCYANATE

Base Information

• Chemical Name: 2-ETHYL-6-METHYLPHENYL ISOTHIOCYANATE
• CAS No.: 66609-04-9
• Molecular Formula: C10H11NS
• Molecular Weight: 177.27
• Hs Code.: 2930909090
• Mol file: 66609-04-9.mol

Synonyms:2-Ethyl-6-methylphenylisothiocyanate;6-Ethyl-o-tolyl isothiocyanate;

Chemical Property of 2-ETHYL-6-METHYLPHENYL ISOTHIOCYANATE

Chemical Property:

• Vapor Pressure: 0.0051mmHg at 25°C
• Refractive Index: 1.6120
• Boiling Point: 284.5 °C at 760 mmHg
• Flash Point: 128.9 °C
• PSA: 44.45000
• Density: 1 g/cm³
• LogP: 3.29170
• Sensitive.: Moisture Sensitive

Purity/Quality:

99% ^*data from raw suppliers

2-Ethyl-6-methylphenyl isothiocyanate ^*data from reagent suppliers

Safty Information:

• Statements: 23/24/25
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-ETHYL-6-METHYLPHENYL ISOTHIOCYANATE

There total 1 articles about 2-ETHYL-6-METHYLPHENYL ISOTHIOCYANATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiophosgene (463-71-8) + 6-ethyl-o-toluidine (24549-06-2) → 2-ethyl-2-methylphenyl isothiocyanate (66609-04-9)

Guidance literature:

With calcium carbonate; In dichloromethane; water;

Reference yield: 66.0%

N-ethylglycine (627-01-0) + 2-ethyl-2-methylphenyl isothiocyanate (66609-04-9) → 1-Ethyl-3-(2-ethyl-6-methylphenyl)-2-thioxo-imidazolidin-4-one

Guidance literature:

With triethylamine; In chloroform; for 18h; Heating;

DOI:10.1021/jm030219z

Reference yield:

2-(2-propylamino)acetic acid (3183-21-9) + 2-ethyl-2-methylphenyl isothiocyanate (66609-04-9) → 3-(2-Ethyl-6-methylphenyl)-1-isopropyl-2-thioxo-imidazolidin-4-one

Guidance literature:

With triethylamine; In chloroform;

upstream raw materials:

thiophosgene

6-ethyl-o-toluidine

Downstream raw materials:

N-(2-Methyl-6-aethyl-phenyl)-N'-tert.-pentyl-thioharnstoff

N-(2-methyl-6-ethyl-phenyl)-N'-tert.-butyl-thiourea

3-[3-(2-ethyl-6-methylphenyl)-1-ethylthioureido]propionic acid

1-(2-ethyl-6-methylphenyl)-(1,2-dideoxy-α-D-glucofurano)[1,2-d]imidazolidine-2-thione