2,5-Piperazinedithione

Base Information

• Chemical Name: 2,5-Piperazinedithione
• CAS No.: 52092-38-3
• Molecular Formula: C4H6N2S2
• Molecular Weight: 146.237
• Hs Code.: 2933599090
• European Community (EC) Number: 633-420-3
• NSC Number: 624856
• DSSTox Substance ID: DTXSID20200080
• Nikkaji Number: J534.728I
• ChEMBL ID: CHEMBL1973563
• Mol file: 52092-38-3.mol

Synonyms:piperazine-2,5-dithione;2,5-Piperazinedithione;Dithiopiperazine;52092-38-3;NSC624856;BRN 0112118;5-24-05-00308 (Beilstein Handbook Reference);CHEMBL1973563;SCHEMBL11897131;DTXSID20200080;AKOS006276506;NSC-624856;NCI60_007559;LS-111987

Chemical Property of 2,5-Piperazinedithione

Chemical Property:

• Vapor Pressure: 0.0169mmHg at 25°C
• Boiling Point: 254.8°C at 760 mmHg
• Flash Point: 107.9°C
• PSA: 102.32000
• Density: 1.42g/cm³
• LogP: -0.47220
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 145.99724055
• Heavy Atom Count: 8
• Complexity: 116

Purity/Quality:

2,5-PIPERAZINEDITHIONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1C(=S)NCC(=S)N1

Technology Process of 2,5-Piperazinedithione

There total 6 articles about 2,5-Piperazinedithione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

glycine (56-40-6,18875-39-3,25718-94-9) → 2,5-piperazinedithione (52092-38-3)

Guidance literature:

With pyridin-1-ium-1-yl[pyridin-1-ium-1-yl(sulfido)phosphinothioyl]sulfanyl-sulfido-thioxo-phosphane; In dimethylsulfone; at 165 - 175 ℃; for 0.25h;

DOI:10.1021/jo101865y

Reference yield: 92.0%

→ 2,5-piperazinedithione (52092-38-3)

Guidance literature:

Reference yield: 90.0%

Glycine anhydride (106-57-0) → 2,5-piperazinedithione (52092-38-3)

Guidance literature:

With pyridin-1-ium-1-yl[pyridin-1-ium-1-yl(sulfido)phosphinothioyl]sulfanyl-sulfido-thioxo-phosphane; In acetonitrile; for 2h; Reflux;

DOI:10.1021/jo101865y

upstream raw materials:

Glycine anhydride

3,6-Bis(methylthio)-2,5-dihydropyridazin

glycylglycine

glycine

Downstream raw materials:

hydrogen sulfide

glycine