2-Hydroxy-N-(O-hydroxybenzylidene) ethyl amine

Base Information

• Chemical Name: 2-Hydroxy-N-(O-hydroxybenzylidene) ethyl amine
• CAS No.: 1952-38-1
• Molecular Formula: C9H11 N O2
• Molecular Weight: 165.192
• Hs Code.: 2925290090
• Mol file: 1952-38-1.mol

Synonyms:Ethanol,2-(salicylideneamino)- (7CI,8CI);(2-Hydroxyethyl)[(2-hydroxyphenyl)methylene]amine; 2-(Salicylidenamino)ethanol;2-(Salicylideneamino)ethanol; 2-[[(2-Hydroxyethyl)imino]methyl]phenol;N-(2-Hydroxyethyl)salicylaldimine; N-(2-Hydroxyethyl)salicylidenamine;N-(2-Hydroxyethyl)salicylidenimine; N-Salicylidene-2-aminoethanol; NSC 4103;Salicylidene-2-ethanolamine; b-(Salicylidenamino)ethanol

Chemical Property of 2-Hydroxy-N-(O-hydroxybenzylidene) ethyl amine

Chemical Property:

• Vapor Pressure: 3.25E-06mmHg at 25°C
• Boiling Point: 347.7°Cat760mmHg
• Flash Point: 164.1°C
• PSA: 52.82000
• Density: 1.274g/cm³
• LogP: 0.80340

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Hydroxy-N-(O-hydroxybenzylidene) ethyl amine

There total 8 articles about 2-Hydroxy-N-(O-hydroxybenzylidene) ethyl amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-methyl-benzyl alcohol (89-95-2) + ethanolamine (141-43-5) → (E)-2-(((2-hydroxyethyl)imino)methyl)phenol (1952-38-1)

Guidance literature:

In benzene; for 0.5h; Heating;

DOI:10.1016/S0022-328X(99)00054-6

Reference yield: 88.0%

salicylaldehyde (90-02-8) + ethanolamine (141-43-5) → 2-[(2-hydroxyethyl)iminomethyl]phenol (1952-38-1)

Guidance literature:

With toluene-4-sulfonic acid; In ethanol; at 60 ℃; for 24h;

DOI:10.1016/j.jorganchem.2018.07.034

Reference yield: 74.0%

salicylaldehyde (90-02-8) + ethanolamine (141-43-5) → (E)-2-(((2-hydroxyethyl)imino)methyl)phenol (1952-38-1)

Guidance literature:

for 3h; Reflux;

DOI:10.1080/14756366.2016.1220375

upstream raw materials:

salicylaldehyde

ethanolamine

butan-1-ol

benzene

Downstream raw materials:

(bis-N-(2-hydroxyethyl)salicylaldiminato) copper(II)

Refernces

• 1、 Paul, Lydia E.H.,Foehn, Ines C.,Schwarzer, Anke,Brendler, Erica,B?hme, Uwe. "Salicylaldehyde-(2-hydroxyethyl)imine - A flexible ligand for group 13 and 14 elements". . p. 268 - 280. Retrieved 2014.
• 2、 Basak, Dipmalya,Martí, Emma Regincós,Murrie, Mark,Nemec, Ivan,Ray, Debashis. "Solvent-induced structural transformation from heptanuclear to decanuclear [Co-Ln] coordination clusters: trapping of unique counteranion and understanding of aggregation pathways". . p. 9574 - 9588. Retrieved 2021.
• 3、 Goodson,Christopher. "-". . p. 1117. Retrieved 1949.
• 4、 Basak, Dipmalya,Gupta, Tulika,K?gerler, Paul,Ray, Debashis,van Leusen, Jan. "Synthetic diversity and change in nuclearity in [Co-Dy] coordination aggregates: bridge removal, solvent induced structural reorganization and AC susceptibility measurements". . p. 7576 - 7591. Retrieved 2020/06/21.
• 5、 Tshabalala, Thandeka A.,Ojwach, Stephen O.. "Hydrogenation of alkenes and alkynes catalysed by N?O (imino)phenol palladium(II) complexes: Structural, kinetics and chemoselectivity studies". . p. 35 - 42. Retrieved 2018/08/21.