Difluorodiphenylmethane

Base Information

• Chemical Name: Difluorodiphenylmethane
• CAS No.: 360-11-2
• Molecular Formula: C13H10F2
• Molecular Weight: 204.219
• Hs Code.: 2903999090
• DSSTox Substance ID: DTXSID10189557
• Nikkaji Number: J403.355H
• Wikidata: Q83061691
• Mol file: 360-11-2.mol

Synonyms:Difluorodiphenylmethane;360-11-2;[difluoro(phenyl)methyl]benzene;Difluoro diphenyl methane;Benzene,1,1'-(difluoromethylene)bis-;Benzene, 1,1'-(difluoromethylene)bis-;SCHEMBL1108511;DTXSID10189557;LVTDRHCAWKTYCQ-UHFFFAOYSA-N;MFCD03788490;AKOS025117100;CS-0069391;FT-0624921;A823092

Chemical Property of Difluorodiphenylmethane

Chemical Property:

• Boiling Point: 268 °C at 760 mmHg
• Flash Point: 95.8 °C
• PSA: 0.00000
• Density: 1.13 g/cm³
• LogP: 3.82670
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 204.07505664
• Heavy Atom Count: 15
• Complexity: 169

Purity/Quality:

98%,99%, ^*data from raw suppliers

DIFLUORODIPHENYLMETHANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(F)F

Technology Process of Difluorodiphenylmethane

There total 34 articles about Difluorodiphenylmethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzophenone hydrazone (5350-57-2) → difluorodiphenylmethane (360-11-2)

Guidance literature:

With pyridine*BrF₃; at 0 ℃;

DOI:10.1021/ol3000348

Reference yield: 95.0%

2,2-diphenyl-1,3-dithiolane (6317-10-8) → difluorodiphenylmethane (360-11-2)

Guidance literature:

With nitrosonium tetrafluoroborate; pyridine hydrogenfluoride; In dichloromethane; for 1h; Ambient temperature;

DOI:10.1016/0040-4020(95)00864-5

Reference yield: 89.0%

Thiobenzophenon (1450-31-3) → difluorodiphenylmethane (360-11-2)

Guidance literature:

With antimony(III) chloride; (bis-(2-methoxyethyl)amino)sulfur trufluoride; In dichloromethane; at 20 ℃; for 48h;

DOI:10.1021/jo000020j

upstream raw materials:

Dichlorodiphenylmethane

benzophenone

2,2-diphenyl-1,3-dithiolane

Benzophenone oxime

Downstream raw materials:

methyl 2,2-diphenylacetate

methyl 2-fluoro-2,2-diphenylacetate

C₁₃H₉BrF₂

Diphenylmethane

Refernces

• 1、 Shida, Naoki,Takenaka, Hiroaki,Gotou, Akihiro,Isogai, Tomohiro,Yamauchi, Akiyoshi,Kishikawa, Yosuke,Nagata, Yuuya,Tomita, Ikuyoshi,Fuchigami, Toshio,Inagi, Shinsuke. "Alkali Metal Fluorides in Fluorinated Alcohols: Fundamental Properties and Applications to Electrochemical Fluorination". . p. 16128 - 16133. Retrieved 2021/07/26.
• 2、 Xu, Zhi-Wei,Zhang, Wei,Lin, Jin-Hong,Jin, Chuan-Ming,Xiao, Ji-Chang. "Pd-Catalyzed Transfer of Difluorocarbene for Three Component Cross-Coupling?". supporting information. p. 1647 - 1650. Retrieved 2020/10/19.