Azelaoyl chloride

Base Information

• Chemical Name: Azelaoyl chloride
• CAS No.: 123-98-8
• Molecular Formula: C9H14Cl2O2
• Molecular Weight: 225.115
• Hs Code.: 29171390
• European Community (EC) Number: 204-668-6
• NSC Number: 519866
• UNII: NEG67YB85G
• DSSTox Substance ID: DTXSID7059561
• Nikkaji Number: J207.918F
• Wikipedia: Azelaoyl_chloride
• Wikidata: Q63179527
• ChEMBL ID: CHEMBL1728994
• Mol file: 123-98-8.mol

Synonyms:Azelaoyl chloride;Nonanedioyl dichloride;123-98-8;Azelayl chloride;Azelaic acid dichloride;Azeoloyl chloride;Azelaic acid chloride;Azelaoylchloride;NEG67YB85G;EINECS 204-668-6;NSC 519866;NSC-519866;Nonanedioyl chloride;azeloylchloride;Nonanedioic dichloride;Azelaoyl Chloride, 98%;UNII-NEG67YB85G;SCHEMBL687819;Azelaic acid dichloride, 98%;CHEMBL1728994;DTXSID7059561;MFCD00000767;NSC519866;AKOS000121289;NCGC00166089-01;BS-42105;A0562;FT-0631721;EN300-21352;D88278;A805182;Azelaic acid dichloride, puriss., >=98.5% (GC);J-005017

Chemical Property of Azelaoyl chloride

Chemical Property:

• Appearance/Colour: clear yellow-brown liquid
• Vapor Pressure: 0.00195mmHg at 25°C
• Refractive Index: n20/D 1.467(lit.)
• Boiling Point: 291.5 °C at 760 mmHg
• Flash Point: 138.9 °C
• PSA: 34.14000
• Density: 1.159 g/cm³
• LogP: 3.24790
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 8
• Exact Mass: 224.0370851
• Heavy Atom Count: 13
• Complexity: 151

Purity/Quality:

97% ^*data from raw suppliers

Azelaoyl Chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34-37
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(CCCC(=O)Cl)CCCC(=O)Cl
• Uses: Organic synthesis. Azelaic acid dichloride (Azelaoyl chloride) was used in synthesis of:series of electrochromic polyamides (alternating copolymers)1,9-diphenylnonane-1,9-dione1,9-di(4-butylphenyl)nonane-1,9-dione

Technology Process of Azelaoyl chloride

There total 2 articles about Azelaoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

azelaic acid (123-99-9,26776-28-3) → azelaoyl chloride (123-98-8)

Guidance literature:

With thionyl chloride; at 80 ℃; for 36h; Inert atmosphere;

DOI:10.1055/s-0037-1611530

Reference yield:

→ azelaoyl chloride (123-98-8)

Guidance literature:

Reference yield: 96.0%

1,2-dimethoxybenzene (91-16-7) + azelaoyl chloride (123-98-8) → 1,9-bis(3,4-dimethoxyphenyl)-1,8-nonanedione (50766-17-1)

Guidance literature:

With aluminum (III) chloride; In dichloromethane; at -10 - 0 ℃; for 6h;

DOI:10.1016/j.tetlet.2009.03.009

upstream raw materials:

azelaic acid

Downstream raw materials:

1,9-bis-(4-bromo-phenyl)-nonane-1,9-dione

1,9-bis(3,4-dimethoxyphenyl)-1,8-nonanedione

9-(3,4-dimethoxy-phenyl)-9-oxo-nonanoic acid

nonanedioic acid bis-[4-(2-diethylamino-ethoxy)-anilide]; dihydrochloride