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Menaquinone-9

Base Information
  • Chemical Name:Menaquinone-9
  • CAS No.:523-39-7
  • Molecular Formula:C56H80O2
  • Molecular Weight:785.25
  • Hs Code.:
  • UNII:Z3YR8XD3W8
  • DSSTox Substance ID:DTXSID001317587
  • Nikkaji Number:J28.570F
  • Metabolomics Workbench ID:29091
  • Mol file:523-39-7.mol
Menaquinone-9

Synonyms:menaquinone 9;menaquinone-9

Suppliers and Price of Menaquinone-9
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Menaquinone9
  • 2mg
  • $ 90.00
  • Crysdot
  • 2-Methyl-3-((2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-yl)naphthalene-1,4-dione 97%
  • 50mg
  • $ 450.00
  • Crysdot
  • 2-Methyl-3-((2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-yl)naphthalene-1,4-dione 97%
  • 25mg
  • $ 305.00
  • Chemenu
  • 2-methyl-3-((2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-yl)naphthalene-1,4-dione 97%
  • 50mg
  • $ 421.00
  • Cayman Chemical
  • Menaquinone 9 ≥95%
  • 25mg
  • $ 550.00
  • Cayman Chemical
  • Menaquinone 9 ≥95%
  • 10mg
  • $ 251.00
  • Cayman Chemical
  • Menaquinone 9 ≥95%
  • 1mg
  • $ 32.00
  • Cayman Chemical
  • Menaquinone 9 ≥95%
  • 5mg
  • $ 142.00
  • Biosynth Carbosynth
  • Menaquinone 9
  • 5 mg
  • $ 110.00
  • Biosynth Carbosynth
  • Menaquinone 9
  • 2 mg
  • $ 60.00
Total 36 raw suppliers
Chemical Property of Menaquinone-9
Chemical Property:
  • Vapor Pressure:3.97E-26mmHg at 25°C 
  • Melting Point:60-61 °C 
  • Refractive Index:1.529 
  • Boiling Point:807.6 °C at 760 mmHg 
  • Flash Point:280.5 °C 
  • PSA:34.14000 
  • Density:0.949 g/cm3 
  • LogP:17.16030 
  • Storage Temp.:Amber Vial, -20?C Freezer 
  • Solubility.:Benzene (Slightly), Chloroform (Slightly), Ethyl Acetate (Slightly) 
  • XLogP3:18.2
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:2
  • Rotatable Bond Count:26
  • Exact Mass:784.61583179
  • Heavy Atom Count:58
  • Complexity:1630
Purity/Quality:

99%, *data from raw suppliers

Menaquinone9 *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC1=C(C(=O)C2=CC=CC=C2C1=O)CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C
  • Isomeric SMILES:CC1=C(C(=O)C2=CC=CC=C2C1=O)C/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CCC=C(C)C
  • Description Menaquinone 9 (MK-9) is a vitamin K2 analog that has been found in various bacteria, including E. coli. MK-9 is UV-sensitive and binds to soluble nitrate reductase, a component of the bacterial electron transport chain. In vivo, MK-9 increases plasma prothrombin concentration in vitamin K-deficient rats.
  • Uses Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a vari ety of physiological processes. Menaquinone 9 is a form of vitamin K2 which acts as a prothrombogenic agent and is also a functional electron transfer component in nitrate reductase. Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a variety of physiological processes. Menaquinone 9 is a form of vitamin K2 which acts as a prothrombogenic agent and is also a functional electron transfer component in nitrate reductase. Vitamin (prothrombogenic).
Technology Process of Menaquinone-9

There total 6 articles about Menaquinone-9 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
solanesyl bromide; 4a-methyl-1,4,4a,9a-tetrahydro-1,4-methanoanthracene-9,10-dione; With 18-crown-6 ether; potassium tert-butylate; In toluene; at 15 ℃; for 6h; Inert atmosphere;
With N-methyl-tri-n-butyl-ammonium bromide; acetic acid; In toluene; at 120 ℃; Inert atmosphere;
DOI:10.1016/j.tet.2020.131696
Guidance literature:
Multi-step reaction with 3 steps
1: PBr3 / pyridine
2: (i) Mg, Et2O, (ii) /BRN= 2066988/
3: AgO, HNO3 / H2O; dioxane
With silver(II) oxide; nitric acid; phosphorus tribromide; In 1,4-dioxane; pyridine; water;
DOI:10.1021/ja00833a035
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