52610-77-2

Basic information

• Product Name: SOLANESYL BROMIDE
• Synonyms: SOLANESYL BROMIDE;(2E,6E,10E,14E,18E,22E,26E,30E)-1-BroMo-3,7,11,15,19,23,27,31,35-nonaMethyl-;2,6,10,14,18,22,26,30,34-hexatriacontanonaene;trans-Solanesyl BroMide
• CAS NO: 52610-77-2
• Molecular Formula: C₄₅H₇₃Br
• Molecular Weight: 693.97
• Product Categories: Nicotine Derivatives
• Mol File: 52610-77-2.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 692.3°C at 760 mmHg
• Flash Point: 370.2°C
• Appearance: /
• Density: 0.956g/cm³
• Vapor Pressure: 3.16E-18mmHg at 25°C
• Refractive Index: 1.511
• Storage Temp.: -20°C Freezer
• Solubility: Benzene (Slightly), Chloroform (Slightly)
• Stability: Light Sensitive
• CAS DataBase Reference: SOLANESYL BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: SOLANESYL BROMIDE(52610-77-2)
• EPA Substance Registry System: SOLANESYL BROMIDE(52610-77-2)

Safety Data

• Hazardous Substances Data: 52610-77-2(Hazardous Substances Data)

Usage

Chemical Properties

Light Brown Solid

Uses

Solanesyl (S676500) derivative, a high molecular weight isoprenoid alcohol isolated from tobacco leaf.

InChI:InChI=1/C45H73Br/c1-37(2)19-11-20-38(3)21-12-22-39(4)23-13-24-40(5)25-14-26-41(6)27-15-28-42(7)29-16-30-43(8)31-17-32-44(9)33-18-34-45(10)35-36-46/h19,21,23,25,27,29,31,33,35H,11-18,20,22,24,26,28,30,32,34,36H2,1-10H3/b38-21+,39-23+,40-25+,41-27+,42-29+,43-31+,44-33+,45-35+

Upstream product

• 28072-21-1 isosolanesol 
• 13190-97-1 solanesol 

Downstream Products

• 83626-12-4 Acetic acid 2,3,6-trimethyl-4-((2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35-nonamethyl-hexatriaconta-2,6,10,14,18,22,26,30,34-nonaenyloxy)-phenyl ester 
• 73875-24-8 6-(4-phenylsulfonyl-3,7,11,15,19,23,27,31,35,39-decamethyl-tetraconta-2,6,10,14,18,22,26,30,34-decaenyl)-2,3-dimethoxy-5-methylhydroquinone bis(2-methoxyethoxymethyl) ether 
• 103669-59-6 N-(2,3,4,5,6-Penta-O-acetyl-D-gluconoyl)-DL-2-phenylglycinsolanesylester 
• 70854-64-7 solanesyl p-tolyl sulphone 
• 15575-04-9 decaprenol 
• 65717-26-2 Solanesylacetone 
• 75426-26-5 ubiquinol 
• 83110-38-7 1-((2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl)-3,4-dimethoxy-2,5-bis((2-methoxyethoxy)methoxy)-6-methylbenzene 
• 899809-09-7 C₇₃H₁₀₄O₆S 
• 74813-93-7 4-(benzenesulfonyl)-3,7,11,15,19,23,27,31,35,39-decamethyl-1-[3,4-dimethoxy-2,5-bis(methoxymethoxy)-6-methylphenyl]tetraconta-2,6,10,14,18,22,26,30,34,38-decaene 
• 523-39-7 2-methyl-3-((2E,6E,10E,14E,18E,22E,26E,30E)-3,7,11,15,19,23,27,31,35- nonamethylhexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-yl)naphthalene-1,4-dione 
• 294674-88-7 solanesyl sulphone 

Relevant articles and documents

Solanesol derived therapeutic carriers for anticancer drug delivery

Metabolites of a large number of inert drug carriers can cause long-term exogenous biological toxicity. Therefore, carriers with simultaneous therapeutic effects may be a good choice for drug delivery. Herein, a series of pharmacologically active solaneso

Synthesis of [3′-14C] coenzyme Q10

Radio-labelled coenzyme Q10, labelled at the 3′-position with 14C, was synthesized starting from natural solanesol and ethyl [3-14C] acetoacetate. The radiochemical yield was 8.0% from ethyl [3-14C] acetoacetate

Synergistic factors ensue high expediency in the synthesis of menaquinone [K2] analogue MK-6: Application to access an efficient one-pot protocol to MK-9

Here we report a practical and efficient method for the synthesis of menaquinone vitamin (K2) analog MK-6 in all trans forms through “1 + 5 convergent synthetic approach” of pentaprenyl chloride with monoprenyl menadione derivative. In the synergistic factors, less efficient leaving group/more efficient nucleophile (Cl) in the substrate makes it more prominent reaction by eliminating all Sn2’ side reaction products. Further, the addition of acetic acid in the last step (desulfonation) of reaction sequence removes the limitations of the reactions in terms of cyclized side product (multiple reactions of pentaprenyl alcohol with Et3B), byproduct (Et3B, incendiary compound) formations and their interruption in the tricky purification processes. The utility of this method was further extended to find an efficient one-pot synthesis to MK-9 to the gram scale synthesis. This approach is economical and efficient and avoids the awkward chromatographic separation processes.

Novel Intermediates, Process for Their Preparation and Process for the Preparation of Coq10 Employing the Said Novel Intermediates

The present invention relates to an improved process for the preparation of Coenzyme Q. Coenzyme Q10 or CoQ10 has the chemical name 2-[(all-trans)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaenyl]-5,6-dimethoxy-3-methyl-1,4-benzoquinone and has the formula I. The invention also provides new intermediates useful for the preparation of CoQ10 and processes for their preparation.