1-[4-(benzyloxy)phenyl]-3-(piperidin-1-yl)propan-1-one

Base Information

Chemical Name:1-[4-(benzyloxy)phenyl]-3-(piperidin-1-yl)propan-1-one
CAS No.:51345-82-5
Molecular Formula:C₂₁H₂₅NO₂*ClH
Molecular Weight:359.896
Hs Code.:
Mol file:51345-82-5.mol

Synonyms:1-Propanone,1-[4-(phenylmethoxy)phenyl]-3-(1-piperidinyl)-, hydrochloride (9CI)

Suppliers and Price of 1-[4-(benzyloxy)phenyl]-3-(piperidin-1-yl)propan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-[4-(benzyloxy)phenyl]-3-(piperidin-1-yl)propan-1-one

Chemical Property:

Vapor Pressure:1.56E-09mmHg at 25°C
Boiling Point:484.3°Cat760mmHg
Flash Point:246.7°C
Density:1.093g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-[4-(benzyloxy)phenyl]-3-(piperidin-1-yl)propan-1-one

There total 3 articles about 1-[4-(benzyloxy)phenyl]-3-(piperidin-1-yl)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51345-81-4
1-<4-(benzyloxy)phenyl>-3-piperidinopropan-1-one

: 51345-82-5
1-<4-(benzyloxy)phenyl>-3-piperidinopropan-1-one hydrochloride

Guidance literature:: With hydrogenchloride; In diethyl ether; Inert atmosphere;
DOI:10.3390/ijms21207708

Reference yield:

: 405212-52-4
N-methoxy-N-methyl-3-(piperidine-1-yl)propanamide

: 51345-82-5
1-<4-(benzyloxy)phenyl>-3-piperidinopropan-1-one hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: tert.-butyl lithium / pentane; tetrahydrofuran / 0.33 h / -78 °C / Inert atmosphere

1.2: 5 h / -78 °C / Inert atmosphere

2.1: hydrogenchloride / diethyl ether / Inert atmosphere

With hydrogenchloride; tert.-butyl lithium; In tetrahydrofuran; diethyl ether; pentane;
DOI:10.3390/ijms21207708