Geiparvarin

Base Information

• Chemical Name: Geiparvarin
• CAS No.: 36413-91-9
• Molecular Formula: C₁₉H₁₈O₅
• Molecular Weight: 326.349
• NSC Number: 142227
• UNII: O0M5JB2L95
• DSSTox Substance ID: DTXSID201026772
• Nikkaji Number: J326.047J
• Wikipedia: Geiparvarin
• Wikidata: Q5530160
• Pharos Ligand ID: B9AVCD81UAUJ
• ChEMBL ID: CHEMBL56918
• Mol file: 36413-91-9.mol

Synonyms:geiparvarin

Chemical Property of Geiparvarin

Chemical Property:

• Vapor Pressure: 1.92E-11mmHg at 25°C
• Melting Point: 158-159 °C(Solv: methanol (67-56-1))
• Boiling Point: 533.1°Cat760mmHg
• Flash Point: 304.7°C
• PSA: 65.74000
• Density: 1.242g/cm³
• LogP: 3.37990
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 326.11542367
• Heavy Atom Count: 24
• Complexity: 626

Purity/Quality:

99% ^*data from raw suppliers

GEIPARVARIN 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=CCOC1=CC2=C(C=C1)C=CC(=O)O2)C3=CC(=O)C(O3)(C)C
• Isomeric SMILES: C/C(=C\COC1=CC2=C(C=C1)C=CC(=O)O2)/C3=CC(=O)C(O3)(C)C

Technology Process of Geiparvarin

There total 68 articles about Geiparvarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-acetoxy-5-<(E)-3-(2-oxo-2H-chromen-7-yloxy)-1-methyl-1-propenyl>-2,2-dimethyl-2,5-dihydrofuran (78957-41-2) → geiparvarin (36413-91-9)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In benzene; at 25 ℃; for 1.8h;

DOI:10.1246/bcsj.56.3078

Reference yield: 96.0%

7-<<(E)-6-amino-7-hydroxy-3,7-dimethyl-4-oxo-2,5-octadienyl>oxy>-2H-1-benzopyran-2-one (101417-86-1) → geiparvarin (36413-91-9)

Guidance literature:

With acetic acid; at 0 ℃; for 4h;

DOI:10.1016/S0040-4039(00)95027-5

Reference yield: 95.0%

7-<<3-(4,5-dihydro-5,5-dimethyl-4-oxo-2-furanyl)-2-hydroxybutyryl>oxy>-2H-1-benzopyran-2-one (477934-89-7) → geiparvarin (36413-91-9)

Guidance literature:

With methanesulfonyl chloride; triethylamine; In tetrahydrofuran;

DOI:10.1016/S0960-894X(02)00798-9

upstream raw materials:

7-hydroxy-2H-chromen-2-one

5-<(E)-3-methanesulfonyloxy-1-methylpropenyl>-2,2-dimethylfuran-3(2H)-one

5-((E)-3-Bromo-1-methyl-propenyl)-2,2-dimethyl-furan-3-one

carbon dioxide