NSC97553

Base Information

• Chemical Name: NSC97553
• CAS No.: 4439-56-9
• Molecular Formula: C11H11NO
• Molecular Weight: 173.214
• Mol file: 4439-56-9.mol

Synonyms:Furfurylamine,N-phenyl- (6CI,8CI);Benzenamine, N-(2-furanylmethyl)-;N-(2-Furanylmethyl)aniline;N-Furfurylaniline;N-Phenylfurfurylamine;NSC 97553;

Chemical Property of NSC97553

Chemical Property:

• Vapor Pressure: 0.00366mmHg at 25°C
• Refractive Index: 1.607
• Boiling Point: 281 °C at 760 mmHg
• Flash Point: 123.7 °C
• PSA: 25.17000
• Density: 1.136 g/cm³
• LogP: 2.96470

Purity/Quality:

99% ^*data from raw suppliers

N-Furfurylaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of NSC97553

There total 51 articles about NSC97553 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

furfural (98-01-1) + aniline (62-53-3) → N-(furan-2-ylmethyl)aniline (4439-56-9)

Guidance literature:

With hydrogen; at 100 ℃; for 0.5h; under 3000.3 Torr; Catalytic behavior;

DOI:10.1016/j.jcat.2020.06.036

Reference yield: 100.0%

(2-furyl)methyl alcohol (98-00-0,25212-86-6,93793-62-5) + aniline (62-53-3) → N-(furan-2-ylmethyl)aniline (4439-56-9)

Guidance literature:

With dichloro-[1,3-bis(4-methylbenzyl)perhydrobenzimidazol-2-ylidene](p-cymene)ruthenium(II); potassium tert-butylate; at 120 ℃; for 24h; Reagent/catalyst; Inert atmosphere; Schlenk technique; Sealed tube;

DOI:10.1016/j.poly.2019.114234

Reference yield: 99.0%

(2-furyl)methyl alcohol (98-00-0,25212-86-6,93793-62-5) + N-phenyltriphenyliminophosphorane (2325-27-1) → N-(furan-2-ylmethyl)aniline (4439-56-9)

Guidance literature:

With cesium hydroxide; palladium diacetate; In toluene; at 150 ℃; for 48h;

DOI:10.1055/s-0030-1260238

upstream raw materials:

2-bromomethylfuran

aniline

N-(2-furylmethylene)aniline

furfural

Downstream raw materials:

N-((furan-2-yl)methyl)-N-methylbenzenamine

6-(Furan-2-ylmethyl-phenyl-amino)-3-methyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidine-5-carbaldehyde

4-(((furan-2-ylmethyl)(phenyl)amino)methyl)quinolin-2(1H)-one

Refernces

• 1、 Beller, Matthias,Gawande, Manoj B.,Jagadeesh, Rajenahally V.,Kadam, Ravishankar G.,Li, Xinmin,Ma, Zhuang,Petr, Martin,Zbo?il, Radek,Zhou, Bei. "Reusable Co-nanoparticles for general and selectiveN-alkylation of amines and ammonia with alcohols". . p. 111 - 117. Retrieved 2022/01/06.
• 2、 Fan, Qing-Hua,Liu, Xintong,Luo, Zhenli,Pan, Yixiao,Xu, Lijin,Yang, Ji,Yao, Zhen,Zhang, Xin. "BF3·Et2O as a metal-free catalyst for direct reductive amination of aldehydes with amines using formic acid as a reductant". supporting information. p. 5205 - 5211. Retrieved 2021/07/29.