Phenazine-1-carboxamide

Base Information

• Chemical Name: Phenazine-1-carboxamide
• CAS No.: 550-89-0
• Molecular Formula: C13H9N3O
• Molecular Weight: 223.234
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID10203545
• Nikkaji Number: J11.574F
• Wikidata: Q27131710
• Metabolomics Workbench ID: 62083
• ChEMBL ID: CHEMBL463748
• Mol file: 550-89-0.mol

Synonyms:PA-1-CA cpd;phenazine-1-carboxamide

Chemical Property of Phenazine-1-carboxamide

Chemical Property:

• Appearance/Colour: green-yellow solid
• Vapor Pressure: 3.68E-11mmHg at 25°C
• Melting Point: 242oC
• Boiling Point: 526.1°C at 760 mmHg
• PKA: 14.33±0.30(Predicted)
• Flash Point: 272°C
• PSA: 68.87000
• Density: 1.371g/cm³
• LogP: 2.58220
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 223.074561919
• Heavy Atom Count: 17
• Complexity: 307

Purity/Quality:

99%, ^*data from raw suppliers

Oxychloroaphine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)N=C3C=CC=C(C3=N2)C(=O)N
• Uses: Oxychloroaphine (1-phenazinecarboxamide) is a simple phenazine produced by several species of Pseudomonas. Oxychloroaphine is a weakly active antifungal metabolite that plays a role in the biocontrol of plant diseases by several Pseudomonas strains. Oxychloroaphine and related phenazines are important dereplication standards in discovery research to eliminate leads due to high amounts of weakly potent actives.

Technology Process of Phenazine-1-carboxamide

There total 10 articles about Phenazine-1-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tubermycin B (2538-68-3,102646-59-3) → phenazine-1-carboxamide (550-89-0)

Guidance literature:

With thionyl chloride; und anschliessend Behandeln mit konz.wss.NH₃;

Reference yield:

phenazine-1-carboxylic acid chloride → phenazine-1-carboxamide (550-89-0)

Guidance literature:

With ammonia; In dichloromethane; water; at 20 ℃; Inert atmosphere;

DOI:10.1039/c3ob42416b

Reference yield:

phenazine-1-carboxylic acid methyl ester (3225-19-2) → phenazine-1-carboxamide (550-89-0)

Guidance literature:

With ammonium hydroxide;

upstream raw materials:

tubermycin B

phenazine-1-carboxylic acid methyl ester

5,10-dihydro-phenazine-1-carboxylic acid amide

anthranilic acid

Downstream raw materials:

phenazin-1-ylamine

tubermycin B

Refernces

• 1、 -. "Phenazine compound containing oxazole ring and application of phenazine compound as agricultural fungicide (by machine translation)". Paragraph 0020; 0022. . Retrieved 2019/12/25.
• 2、 -. "PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS". . . Retrieved 2015/07/15.