2H-1-Benzopyran-2-one, 7-methoxy-3-phenyl-4-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-

Base Information

Chemical Name:2H-1-Benzopyran-2-one, 7-methoxy-3-phenyl-4-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-
CAS No.:78994-30-6
Molecular Formula:C28H27NO4
Molecular Weight:441.5183
Hs Code.:
UNII:EY2Y929X1U
DSSTox Substance ID:DTXSID70229483
Wikidata:Q83109762
ChEMBL ID:CHEMBL2413906

Synonyms:2H-1-Benzopyran-2-one, 7-methoxy-3-phenyl-4-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-;78994-30-6;EY2Y929X1U;Coumarin, 7-methoxy-3-phenyl-4-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-;7-Methoxy-3-phenyl-4-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)coumarin;7-Methoxy-3-phenyl-4-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-2H-1-benzopyran-2-one;UNII-EY2Y929X1U;CHEMBL2413906;DTXSID70229483;LS-39783

Suppliers and Price of 2H-1-Benzopyran-2-one, 7-methoxy-3-phenyl-4-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2H-1-Benzopyran-2-one, 7-methoxy-3-phenyl-4-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-

Chemical Property:

Vapor Pressure:1.7E-15mmHg at 25°C
Boiling Point:624.1°C at 760 mmHg
Flash Point:331.2°C
Density:1.22g/cm³
XLogP3:5.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:441.19400834
Heavy Atom Count:33
Complexity:686

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C(=C(C(=O)O2)C3=CC=CC=C3)C4=CC=C(C=C4)OCCN5CCCC5

Technology Process of 2H-1-Benzopyran-2-one, 7-methoxy-3-phenyl-4-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-

There total 2 articles about 2H-1-Benzopyran-2-one, 7-methoxy-3-phenyl-4-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 123-75-1
pyrrolidine

: 1450604-26-8
4-(4-(2-bromoethoxy)phenyl)-7-methoxy-3-phenyl-2H-chromen-2-one

: 78994-30-6
4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-7-methoxy-3-phenyl-2H-chromen-2-one

Guidance literature:: In tetrahydrofuran; at 120 ℃; for 0.5h; Microwave irradiation; Sealed tube;
DOI:10.1016/j.bmcl.2013.07.009

Reference yield:

: 33257-83-9
4-(4-hydroxyphenyl)-7-methoxy-3-phenyl-2H-chromen-2-one

: 78994-30-6
4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-7-methoxy-3-phenyl-2H-chromen-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 0.5 h / 130 °C / Microwave irradiation; Sealed tube

2: tetrahydrofuran / 0.5 h / 120 °C / Microwave irradiation; Sealed tube

With potassium carbonate; In tetrahydrofuran; acetone;
DOI:10.1016/j.bmcl.2013.07.009