Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dimethoxy-

Base Information

Chemical Name:Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dimethoxy-
CAS No.:36886-76-7
Molecular Formula:C22H16 O5
Molecular Weight:360.366
Hs Code.:2932999099
European Community (EC) Number:253-255-7
UNII:VR6T85J6PC
DSSTox Substance ID:DTXSID2068006
Nikkaji Number:J68.996C
Wikidata:Q81994699
Mol file:36886-76-7.mol

Synonyms:36886-76-7;3',6'-Dimethoxyfluoran;Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dimethoxy-;3',6'-Dimethoxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one;3',6'-dimethoxyspiro[2-benzofuran-3,9'-xanthene]-1-one;EINECS 253-255-7;3,6-DIMETHOXYFLUORAN;3',6'-Dimethoxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one;Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 3',6'-dimethoxy-;3',6'-Dimethoxyspiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one;3',6'-dimethoxyspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one;VR6T85J6PC;SCHEMBL1930643;DTXSID2068006;MFCD08276350;D3205;F71382

Suppliers and Price of Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dimethoxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3',6'-Dimethoxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one 97%
500g
$ 860.00

Biosynth Carbosynth
3',6'-Dimethoxyfluoran
250 g
$ 950.00

Biosynth Carbosynth
3',6'-Dimethoxyfluoran
100 g
$ 460.00

Biosynth Carbosynth
3',6'-Dimethoxyfluoran
50 g
$ 240.00

Biosynth Carbosynth
3',6'-Dimethoxyfluoran
25 g
$ 125.00

Biosynth Carbosynth
3',6'-Dimethoxyfluoran
10 g
$ 65.00

Aaron Chemicals
3,6-DIMETHOXYFLUORAN 98%
5g
$ 62.00

Aaron Chemicals
3,6-DIMETHOXYFLUORAN 98%
1g
$ 20.00

Total 23 raw suppliers

Chemical Property of Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dimethoxy-

Chemical Property:

Melting Point:202 °C
Boiling Point:559.9±50.0 °C(Predicted)
Flash Point:247.2oC
PSA：53.99000
Density:1.40±0.1 g/cm3(Predicted)
LogP:4.27180
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:360.09977361
Heavy Atom Count:27
Complexity:549

Purity/Quality:

98% ^*data from raw suppliers

3',6'-Dimethoxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)OC)C5=CC=CC=C5C(=O)O3

Technology Process of Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dimethoxy-

There total 9 articles about Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dimethoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 77-78-1
dimethyl sulfate

: 2321-07-5,126605-73-0
fluorescein

: 36886-76-7
3′,6′-dimethoxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one

Guidance literature:: fluorescein; With potassium carbonate; In acetone; for 0.5h;

dimethyl sulfate; In acetone; at 50 ℃; for 4h;
DOI:10.1111/cbdd.13367

Reference yield: 89.0%

: 85-44-9
phthalic anhydride

: 150-19-6
O-methylresorcine

: 36886-76-7
3′,6′-dimethoxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one

Guidance literature:: With niobium pentachloride; In methanesulfonic acid; at 95 - 100 ℃; for 1h; Inert atmosphere;
DOI:10.1002/cplu.201600530

Reference yield: 65.0%

: 2321-07-5,126605-73-0
fluorescein

: 74-88-4
methyl iodide

: 36886-76-7
3′,6′-dimethoxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one

Guidance literature:: fluorescein; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Inert atmosphere; Schlenk technique;

methyl iodide; In N,N-dimethyl-formamide; at 70 ℃; for 24h; Inert atmosphere; Schlenk technique;
DOI:10.1002/ejoc.201201093