4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(3-methoxyphenoxy)pyrimidin-4-yl]benzenesulfonamide

Base Information

Chemical Name:4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(3-methoxyphenoxy)pyrimidin-4-yl]benzenesulfonamide
CAS No.:150725-87-4
Molecular Formula:C23H27 N3 O6 S
Molecular Weight:473.55
Hs Code.:
DSSTox Substance ID:DTXSID80164598
Nikkaji Number:J562.238G
Wikidata:Q83033656
ChEMBL ID:CHEMBL115951
Mol file:150725-87-4.mol

Synonyms:4-tert-butyl-N-(6-(2-hydroxyethoxy)-5-(3-methoxyphenoxy)-4-pyrimidinyl)benzenesulfonamide;Ro 46-2005;Ro-46-2005;Ro46-2005

Suppliers and Price of 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(3-methoxyphenoxy)pyrimidin-4-yl]benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
RO462005
1mg
$ 75.00

DC Chemicals
Ro46-2005 >98%
1 g
$ 2100.00

DC Chemicals
Ro46-2005 >98%
250 mg
$ 1100.00

CSNpharm
Ro46-2005
10mg
$ 140.00

Crysdot
Ro46-2005 98+%
50mg
$ 1426.00

Crysdot
Ro46-2005 98+%
25mg
$ 839.00

Crysdot
Ro46-2005 98+%
10mg
$ 475.00

Crysdot
Ro46-2005 98+%
5mg
$ 333.00

ChemScene
Ro46-2005 97.84%
5mg
$ 80.00

ChemScene
Ro46-2005 97.84%
10mg
$ 150.00

Total 10 raw suppliers

Chemical Property of 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(3-methoxyphenoxy)pyrimidin-4-yl]benzenesulfonamide

Chemical Property:

Vapor Pressure:4.15E-16mmHg at 25°C
Boiling Point:617.5°C at 760 mmHg
PKA:0.83±0.10(Predicted)
Flash Point:327.3°C
PSA：128.25000
Density:1.299g/cm³
LogP:4.90070
Storage Temp.:Sealed in dry,Store in freezer, under -20°C
XLogP3:4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:10
Exact Mass:473.16205676
Heavy Atom Count:33
Complexity:687

Purity/Quality:

99%, ^*data from raw suppliers

RO462005 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC=N2)OCCO)OC3=CC=CC(=C3)OC
Uses RO462005 is an endothelin receptor selective agonist.

Technology Process of 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(3-methoxyphenoxy)pyrimidin-4-yl]benzenesulfonamide

There total 1 articles about 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(3-methoxyphenoxy)pyrimidin-4-yl]benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: