4-OXO-4-([3-(TRIFLUOROMETHYL)PHENYL]AMINO)BUTANOIC ACID

Base Information

Chemical Name:4-OXO-4-([3-(TRIFLUOROMETHYL)PHENYL]AMINO)BUTANOIC ACID
CAS No.:15386-93-3
Molecular Formula:C11H10 F3 N O3
Molecular Weight:261.201
Hs Code.:2924299090
Mol file:15386-93-3.mol

Synonyms:Succinanilicacid, 3'-(trifluoromethyl)- (8CI); NSC 203940

Suppliers and Price of 4-OXO-4-([3-(TRIFLUOROMETHYL)PHENYL]AMINO)BUTANOIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
3'-(TRIFLUOROMETHYL)SUCCINANILIC ACID AldrichCPR
50mg
$ 144.00

Matrix Scientific
N-(3-Trifluoromethyl-phenyl)-succinamic acid 95%+
5g
$ 823.00

Matrix Scientific
N-(3-Trifluoromethyl-phenyl)-succinamic acid 95%+
2.500g
$ 544.00

Matrix Scientific
N-(3-Trifluoromethyl-phenyl)-succinamic acid 95%+
1g
$ 251.00

Total 9 raw suppliers

Chemical Property of 4-OXO-4-([3-(TRIFLUOROMETHYL)PHENYL]AMINO)BUTANOIC ACID

Chemical Property:

Vapor Pressure:1.89E-08mmHg at 25°C
Boiling Point:438.1°C at 760 mmHg
Flash Point:218.8°C
PSA：66.40000
Density:1.422g/cm³
LogP:2.58170

Purity/Quality:

≥98% ^*data from raw suppliers

3'-(TRIFLUOROMETHYL)SUCCINANILIC ACID AldrichCPR ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-OXO-4-([3-(TRIFLUOROMETHYL)PHENYL]AMINO)BUTANOIC ACID

There total 2 articles about 4-OXO-4-([3-(TRIFLUOROMETHYL)PHENYL]AMINO)BUTANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 108-30-5
succinic acid anhydride

: 98-16-8
3-trifluoromethylaniline

: 15386-93-3
4-oxo-4-[3-(trifluoromethyl)phenylamino]butanoic acid

Guidance literature:: With acetic acid; at 20 ℃;
DOI:10.1134/S1070363217100231

Reference yield:

: 15386-93-3
4-oxo-4-[3-(trifluoromethyl)phenylamino]butanoic acid

Guidance literature:: 3-Trifluormethyl-anilin, 3-Carboxy-propionsaeurechlorid;

Reference yield: 65.0%

: 517-89-5
shikonin

: 15386-93-3
4-oxo-4-[3-(trifluoromethyl)phenylamino]butanoic acid

: (R)-1-(5,8-dihydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-4-methylpent-3-en-1-yl 4-oxo-4-((3-(trifluoromethyl)phenyl)amino)butanoate

Guidance literature:: 4-oxo-4-[3-(trifluoromethyl)phenylamino]butanoic acid; With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 0.5h;

shikonin; In dichloromethane; for 4h; Cooling with ice;
DOI:10.1016/j.bioorg.2021.104872