N-[amino(phenoxy)phosphoryl]-2-chloro-N-(2-chloroethyl)ethanamine

Base Information

• Chemical Name: N-[amino(phenoxy)phosphoryl]-2-chloro-N-(2-chloroethyl)ethanamine
• CAS No.: 18374-36-2
• Molecular Formula: C10H15Cl2N2O2P
• Molecular Weight: 297.121
• NSC Number: 69940
• DSSTox Substance ID: DTXSID80290609
• Mol file: 18374-36-2.mol

Synonyms:18374-36-2;phenyl n,n-bis(2-chloroethyl)phosphorodiamidate;N-[amino(phenoxy)phosphoryl]-2-chloro-N-(2-chloroethyl)ethanamine;N,N-Bis(2-chloroethyl)-phosphorodiamidicAcidPhenylEster;N,N-Bis(2-chloroethyl)-phosphorodiamidic Acid Phenyl Ester;NSC69940;SCHEMBL9452799;DTXSID80290609;NSC-69940;AKOS030255155;Phosphorodiamidic acid,N-bis(2-chloroethyl)-, phenyl ester

Chemical Property of N-[amino(phenoxy)phosphoryl]-2-chloro-N-(2-chloroethyl)ethanamine

Chemical Property:

• Vapor Pressure: 1.02E-06mmHg at 25°C
• Boiling Point: 403.4°C at 760 mmHg
• Flash Point: 197.8°C
• Density: 1.345g/cm³
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 296.0248201
• Heavy Atom Count: 17
• Complexity: 257

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)OP(=O)(N)N(CCCl)CCCl

Technology Process of N-[amino(phenoxy)phosphoryl]-2-chloro-N-(2-chloroethyl)ethanamine

There total 1 articles about N-[amino(phenoxy)phosphoryl]-2-chloro-N-(2-chloroethyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Phenyl-N,N-di(2-chlorethyl)phosphorsaeurediamid (18374-36-2)

Guidance literature:

With ammonia; benzene;

DOI:10.1021/ja01632a007

Reference yield: 95.0%

triphenyl phosphite (101-02-0) + Phenyl-N,N-di(2-chlorethyl)phosphorsaeurediamid (18374-36-2) + 4-nitrobenzaldehdye (555-16-8) → C29H29Cl2N3O7P2 (1152369-06-6)

Guidance literature:

With acetyl chloride; at 20 ℃; for 7h;

DOI:10.1080/10426500701807616

Reference yield: 94.0%

triphenyl phosphite (101-02-0) + Phenyl-N,N-di(2-chlorethyl)phosphorsaeurediamid (18374-36-2) + benzaldehyde (100-52-7) → C29H30Cl2N2O5P2 (1152369-04-4)

Guidance literature:

With acetyl chloride; at 20 ℃; for 6h;

DOI:10.1080/10426500701807616

Downstream raw materials:

N,N-bis(2-chloroethyl)phenylphosphoramidic acid

C₂₄H₂₅Cl₂N₂O₂P

C₁₉H₂₀Cl₂N₃O₂P

phosphoramide mustard