1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N-(1-methylethyl)-3-phenyl-

Base Information

Chemical Name:1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N-(1-methylethyl)-3-phenyl-
CAS No.:87539-92-2
Molecular Formula:C18H17N5
Molecular Weight:303.3611
Hs Code.:
DSSTox Substance ID:DTXSID40236386
Wikidata:Q83118333
ChEMBL ID:CHEMBL13898

Synonyms:BRN 6427517;1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N-(1-methylethyl)-3-phenyl-;N-(1-Methylethyl)-3-phenyl-1,2,4-triazolo(3,4-a)phthalazin-6-amine;87539-92-2;CHEMBL13898;DTXSID40236386;LS-156562

Suppliers and Price of 1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N-(1-methylethyl)-3-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N-(1-methylethyl)-3-phenyl-

Chemical Property:

Density:1.28g/cm³
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:303.14839556
Heavy Atom Count:23
Complexity:395

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)NC1=NN2C(=NN=C2C3=CC=CC=C31)C4=CC=CC=C4

Technology Process of 1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N-(1-methylethyl)-3-phenyl-

There total 4 articles about 1,2,4-Triazolo(3,4-a)phthalazin-6-amine, N-(1-methylethyl)-3-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 56813-54-8
6-chloro-3-phenyl-1,2,4-triazolo[3,4-a]phthalazine

: 75-31-0
isopropylamine

: 87539-92-2
Isopropyl-(3-phenyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-amine

Guidance literature:: With hydrogenchloride; potassium iodide; In ethanol; at 100 ℃; for 8h;
DOI:10.1021/jm00401a010

Reference yield:

: 51935-42-3,59275-72-8
1-chloro-4-hydrazinophthalazine

: 87539-92-2
Isopropyl-(3-phenyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / 0.1N HCl / 0.17 h / 60 °C

2: 74 percent / Br₂, sodium acetate / acetic acid / 1 h / Ambient temperature

3: 54 percent / KI, HCl / ethanol / 8 h / 100 °C

With hydrogenchloride; bromine; sodium acetate; potassium iodide; In ethanol; acetic acid;
DOI:10.1021/jm00401a010

Reference yield:

: 100-52-7
benzaldehyde

: 87539-92-2
Isopropyl-(3-phenyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / 0.1N HCl / 0.17 h / 60 °C

2: 74 percent / Br₂, sodium acetate / acetic acid / 1 h / Ambient temperature

3: 54 percent / KI, HCl / ethanol / 8 h / 100 °C

With hydrogenchloride; bromine; sodium acetate; potassium iodide; In ethanol; acetic acid;
DOI:10.1021/jm00401a010