2-Nitrobenzidine

Base Information

• Chemical Name: 2-Nitrobenzidine
• CAS No.: 2243-78-9
• Molecular Formula: C12H11 N3 O2
• Molecular Weight: 229.238
• Hs Code.: 2921590090
• European Community (EC) Number: 683-703-0
• UNII: C104KU8407
• DSSTox Substance ID: DTXSID4036859
• Nikkaji Number: J7.376H
• Wikidata: Q27894110
• Mol file: 2243-78-9.mol

Synonyms:2-Nitrobenzidine;2243-78-9;4-(4-aminophenyl)-3-nitroaniline;Benzidine, 2-nitro-;4,4'-Diamino-2-nitrobiphenyl;2-Nitrobenzidin;2-Nitrobenzidin [Czech];CCRIS 6586;BRN 2736686;C104KU8407;4-(4-AMINOPHENYL)-3-NITRO-ANILINE;3-13-00-00449 (Beilstein Handbook Reference);[1,1'-Biphenyl]-4,4'-diamine, 2-nitro-;(1,1'-BIPHENYL)-4,4'-DIAMINE, 2-NITRO-;Nitrobenzidin;SCHEMBL474215;DTXSID4036859;UNII-C104KU8407;AKOS004903537;LS-32423;2-NITRO(1,1'-BIPHENYL)-4,4'-DIAMINE;Q27894110

Chemical Property of 2-Nitrobenzidine

Chemical Property:

• Melting Point: 117 °C
• Boiling Point: 429.8°Cat760mmHg
• PKA: 3.90±0.10(Predicted)
• Flash Point: 213.7°C
• PSA: 97.86000
• Density: 1.339g/cm³
• LogP: 4.11180
• XLogP3: 2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 229.085126602
• Heavy Atom Count: 17
• Complexity: 271

Purity/Quality:

99% ^*data from raw suppliers

2-NITROBENZIDINE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C2=C(C=C(C=C2)N)[N+](=O)[O-])N

Technology Process of 2-Nitrobenzidine

There total 11 articles about 2-Nitrobenzidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

p,p'-diaminobiphenyl (92-87-5) → 2-nitro-benzidine (2243-78-9)

Guidance literature:

With sulfuric acid; potassium nitrate; at 15 - 20 ℃; for 1h;

Reference yield:

sulfuric acid (7664-93-9) + p,p'-diaminobiphenyl (92-87-5) → 2-nitro-benzidine (2243-78-9) + 2,2'-dinitrobenzidine (5855-71-0) + 2,3'-dinitrobenzidine (83600-78-6)

Guidance literature:

Reference yield:

→ 2-nitro-benzidine (2243-78-9)

Guidance literature:

With sulfuric acid; potassium nitrate; at 10 - 20 ℃;

upstream raw materials:

N,N'-Diacetylbenzidin

p,p'-diaminobiphenyl

benzidine; sulfate

ammonia

Downstream raw materials:

4,4'-dibromo-2-nitro-biphenyl

amino-2 bis(ethoxycarbonylamino)-4,4' biphenyle

benzamido-2 bis(ethoxycarbonylamino)-4,4' biphenyle

propionamate de methyle