4',7-Dihydroxy-3-methoxy-5,6-dimethylflavone

Base Information

Chemical Name:4',7-Dihydroxy-3-methoxy-5,6-dimethylflavone
CAS No.:132020-55-4
Molecular Formula:C18H16 O5
Molecular Weight:312.32
Hs Code.:
DSSTox Substance ID:DTXSID50157311
Nikkaji Number:J374.249K
Wikidata:Q83025455
ChEMBL ID:CHEMBL350085
Mol file:132020-55-4.mol

Synonyms:4',7-dihydroxy-3-methoxy-5,6-dimethylflavone;4,7-DMDF

Suppliers and Price of 4',7-Dihydroxy-3-methoxy-5,6-dimethylflavone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4',7-DIHYDROXY-3-METHOXY-5,6-DIMETHYLFLAVONE 95.00%
5MG
$ 497.32

Total 1 raw suppliers

Chemical Property of 4',7-Dihydroxy-3-methoxy-5,6-dimethylflavone

Chemical Property:

Boiling Point:586°Cat760mmHg
Flash Point:218.4°C
PSA：79.90000
Density:1.39g/cm³
LogP:3.49660
XLogP3:3.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:312.09977361
Heavy Atom Count:23
Complexity:492

Purity/Quality:: 4',7-DIHYDROXY-3-METHOXY-5,6-DIMETHYLFLAVONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C2=C(C=C1O)OC(=C(C2=O)OC)C3=CC=C(C=C3)O)C

Technology Process of 4',7-Dihydroxy-3-methoxy-5,6-dimethylflavone

There total 3 articles about 4',7-Dihydroxy-3-methoxy-5,6-dimethylflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 132020-83-8
4'-(benzyloxy)-7-hydroxy-3-methoxy-5,6-dimethylflavone

: 132020-55-4
7-Hydroxy-2-(4-hydroxy-phenyl)-3-methoxy-5,6-dimethyl-chromen-4-one

Guidance literature:: With hydrogenchloride; acetic acid; for 3h; Heating;
DOI:10.1021/jm00106a039

Reference yield:

: 1486-49-3
p-(benzyloxy)benzoic acid anhydride

: 132020-55-4
7-Hydroxy-2-(4-hydroxy-phenyl)-3-methoxy-5,6-dimethyl-chromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / potassium p-(benzyloxy)benzoate / 8 h / 160 °C

2: 83 percent / AcOH, HCl / 3 h / Heating

With hydrogenchloride; potassium salt of 4-(phenylmethoxy)benzoic acid; acetic acid;
DOI:10.1021/jm00106a039

Reference yield:

: 132020-84-9
2,4-dihydroxy-β-methoxy-5,6-dimethylacetophenone

: 132020-55-4
7-Hydroxy-2-(4-hydroxy-phenyl)-3-methoxy-5,6-dimethyl-chromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / potassium p-(benzyloxy)benzoate / 8 h / 160 °C

2: 83 percent / AcOH, HCl / 3 h / Heating

With hydrogenchloride; potassium salt of 4-(phenylmethoxy)benzoic acid; acetic acid;
DOI:10.1021/jm00106a039