Suprifen

Base Information

• Chemical Name: Suprifen
• CAS No.: 52671-39-3
• Molecular Formula: C10H15 N O2
• Molecular Weight: 181.235
• European Community (EC) Number: 206-672-3
• DSSTox Substance ID: DTXSID30110025
• Nikkaji Number: J3.031.294E
• Wikipedia: Oxilofrine
• Wikidata: Q1689157
• ChEMBL ID: CHEMBL30400
• Mol file: 52671-39-3.mol

Synonyms:1-(4'-hydroxyphenyl)-2-methylaminopropanol;1-(4-hydroxyphenyl)-2-methylaminopropanol;4-hydroxyephedrine;carnigen;methylsynephrine;oxilofrin;oxilofrin, (R*,R*)-(+-)-isomer;oxilofrin, (R*,S*)-(+-)-isomer;oxilofrin, (R*,S*)-isomer;oxilofrin, (R-(R*,S*))-isomer;oxilofrin, hydrochloride;oxilofrin, hydrochloride, (R*,R*)-(+-)-isomer;oxilofrin, hydrochloride, (R*,S*)-(+-)-isomer;oxilofrin, hydrochloride, (R*,S*)-isomer;oxilofrine;oxilofrine hydrochloride;para-hydroxyephedrine;R-(-)-beta-O-methylsynephrine;suprifen

Chemical Property of Suprifen

Chemical Property:

• Boiling Point: 343.8°Cat760mmHg
• Flash Point: 149.9°C
• PSA: 52.49000
• Density: 1.124g/cm³
• LogP: 1.42440
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 181.110278721
• Heavy Atom Count: 13
• Complexity: 144

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(C1=CC=C(C=C1)O)O)NC

Technology Process of Suprifen

There total 6 articles about Suprifen which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(4-hydroxy-phenyl)-2-methylamino-propan-1-one (132224-98-7) → oxilofrine (365-26-4,34597-44-9,52671-39-3,67381-70-8,85482-66-2,102680-48-8,102734-79-2)

Guidance literature:

With ethanol; nickel; at 100 ℃; under 29420.3 Torr; Hydrogenation;

Reference yield:

→ oxilofrine (365-26-4,34597-44-9,52671-39-3,67381-70-8,85482-66-2,102680-48-8,102734-79-2)

Guidance literature:

With hydrogenchloride; nickel; at 100 ℃; under 29420.3 Torr; Hydrogenation;

Reference yield:

→ oxilofrine (365-26-4,34597-44-9,52671-39-3,67381-70-8,85482-66-2,102680-48-8,102734-79-2)

Guidance literature:

With water; copper;

upstream raw materials:

1-(4-hydroxy-phenyl)-2-methylamino-propan-1-one

methylamine

Downstream raw materials:

4-methoxyphenylacetone