Technology Process of Homoisomelodienone
There total 8 articles about Homoisomelodienone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine;
In
acetonitrile;
at 20 ℃;
for 3h;
Overall yield = 42 percent; Overall yield = 73 mg; stereoselective reaction;
Inert atmosphere;
DOI:10.1039/d1ob00599e
- Guidance literature:
-
With
triethylamine;
In
acetonitrile;
at 20 ℃;
for 3h;
Overall yield = 42 percent; Overall yield = 73 mg; stereoselective reaction;
Inert atmosphere;
DOI:10.1039/d1ob00599e
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere
1.2: 3 h / 0 °C / Inert atmosphere
2.1: manganese(IV) oxide / dichloromethane / 8 h / 20 °C / Inert atmosphere
3.1: lithium diisopropyl amide / tetrahydrofuran / 0.17 h / -78 °C / Inert atmosphere
3.2: 0.5 h / -78 °C / Inert atmosphere
4.1: triethylamine / acetonitrile / 3 h / 20 °C / Inert atmosphere
With
manganese(IV) oxide; sodium hydride; triethylamine; lithium diisopropyl amide;
In
tetrahydrofuran; dichloromethane; acetonitrile;
DOI:10.1039/d1ob00599e
