Hydrindantin

Base Information

• Chemical Name: Hydrindantin
• CAS No.: 5103-42-4
• Molecular Formula: C18H10 O6
• Molecular Weight: 322.274
• Hs Code.: 2914400090
• European Community (EC) Number: 225-823-4
• NSC Number: 83617
• UNII: P469P1DDC0
• DSSTox Substance ID: DTXSID8063701
• Nikkaji Number: J8.809I
• Wikipedia: Hydrindantin
• Wikidata: Q10861006
• Mol file: 5103-42-4.mol

Synonyms:hydrindantin

Chemical Property of Hydrindantin

Chemical Property:

• Vapor Pressure: 5.55E-16mmHg at 25°C
• Melting Point: 252 °C (dec.)(lit.)
• Refractive Index: 1.4800 (estimate)
• Boiling Point: 615°C at 760 mmHg
• PKA: 8.89±0.20(Predicted)
• Flash Point: 339.8°C
• PSA: 108.74000
• Density: 1.718±0.06 g/cm3 (20 ºC 760 Torr)
• LogP: 0.60700
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 322.04773803
• Heavy Atom Count: 24
• Complexity: 546

Purity/Quality:

98%,99%, ^*data from raw suppliers

Hydrindantin ≥97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Uses -> Biochemical Research
• Canonical SMILES: C1=CC=C2C(=C1)C(=O)C(C2=O)(C3(C(=O)C4=CC=CC=C4C3=O)O)O
• Uses: Used in the determination of amino acids.

Technology Process of Hydrindantin

There total 22 articles about Hydrindantin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

indan-1,2,3-trione hydrate (485-47-2) → hydrindantin (5103-42-4)

Guidance literature:

With ascorbic acid; In acetic acid;

Reference yield: 60.0%

indantrione (938-24-9) → hydrindantin (5103-42-4)

Guidance literature:

With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; In acetonitrile; at 20 ℃; for 0.0333333h;

DOI:10.1002/hlca.200490085

Reference yield:

2-Acetoxy-1,3-indandione (73636-26-7) → hydrindantin (5103-42-4)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

indan-1,2,3-trione hydrate

2-nitro-1,3-indanedione

acetic acid

3-(2-Hydroxy-aethoxy)-2-hydroxy-indenon-⁽¹⁾

Downstream raw materials:

phthalic anhydride

[2,2']biindenyl-1,3,1',3'-tetraone

acetaldehyde

Refernces

Facile acid-catalyzed condensation of 2-hydroxy-2,2′-biindan-1, 1′,3,3′-tetrone with phenols, methoxyaromatic systems and enols

10.1016/j.tet.2004.09.004

The research explores the acid-catalyzed condensation reactions of 2-hydroxy-2,20-biindan-1,10,3,30-tetrone with various phenols, methoxyaromatic systems, and enols. The purpose of this study is to investigate the electrophilic chemistry of 2-hydroxy-2,2-biindan-1,10,3,30-tetrone, a partially reduced derivative of hydrindantin, which is more stable in acidic conditions compared to hydrindantin itself. The researchers found that this compound readily reacts with a range of substrates to form 2-aryl/alkyl-2,20-biindan-1,10,3,30-tetrones and chromenes in high yields. Notably, resorcinol, 1,3,5-trihydroxybenzene, and a- and b-naphthols preferentially form intramolecular hemi-ketal structures, as confirmed by X-ray diffraction studies.