(3E)-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)furan-2(3H)-one

Base Information

Chemical Name:(3E)-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)furan-2(3H)-one
CAS No.:145588-13-2
Molecular Formula:C₁₇H₁₂O₆
Molecular Weight:312.279
Hs Code.:
DSSTox Substance ID:DTXSID401137371
Nikkaji Number:J576.180H
Wikidata:Q27133917
Metabolomics Workbench ID:63911

Synonyms:3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)-2(3H)-furanone;BE 23372M;BE-23372M

Suppliers and Price of (3E)-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)furan-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (3E)-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)furan-2(3H)-one

Chemical Property:

Vapor Pressure:3.35E-20mmHg at 25°C
Boiling Point:699.2°C at 760 mmHg
Flash Point:265°C
Density:1.616g/cm³
XLogP3:2.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:312.06338810
Heavy Atom Count:23
Complexity:525

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C=C2C=C(OC2=O)C3=CC(=C(C=C3)O)O)O)O
Isomeric SMILES:C1=CC(=C(C=C1/C=C/2\C=C(OC2=O)C3=CC(=C(C=C3)O)O)O)O

Technology Process of (3E)-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)furan-2(3H)-one

There total 10 articles about (3E)-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)furan-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.3%

: 155787-75-0
(E)-4-(4-(3,4-diacetoxybenzylidene)-5-oxo-4,5-dihydrofuran-2-yl)-1,2-phenylene diacetate

: 145588-13-2
(E)-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)-2(3H)-furanone

Guidance literature:: With ammonium hydroxide; In acetone; for 15h; Ambient temperature;
DOI:10.7164/antibiotics.47.297

Reference yield:

: 5333-34-6
3-(3,4-dimethoxybenzoyl)propionic acid

: 145588-13-2
(E)-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)-2(3H)-furanone

Guidance literature:: Multi-step reaction with 2 steps

1: 66.4 percent / acetic anhydride / 1,2-dichloro-ethane / 15 h / 80 °C

2: 1.) NaOAc, 2.) 1M BBr₃ / 1.) acetic anhydride, 80 deg C, 6 h, 2.) CH₂Cl₂, r.t., 15 h

With sodium acetate; acetic anhydride; boron tribromide; In 1,2-dichloro-ethane;
DOI:10.7164/antibiotics.47.297

Reference yield:

: 4-((E)-3-(((Z)-1-(3,4-diacetoxyphenyl)-2-iodovinyl)oxy)-3-oxoprop-1-en-1-yl)-1,2-phenylene diacetate

: 145588-13-2
(E)-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)-2(3H)-furanone

Guidance literature:: Multi-step reaction with 2 steps

1: palladium diacetate; potassium acetate / N,N-dimethyl-formamide / 64 h / 20 °C

2: ammonium hydroxide

With ammonium hydroxide; potassium acetate; palladium diacetate; In N,N-dimethyl-formamide; 1: |Heck Reaction;
DOI:10.1039/c8ob02063a