Quinoline, 8,8'-dithiobis-

Base Information

• Chemical Name: Quinoline, 8,8'-dithiobis-
• CAS No.: 1160-28-7
• Deprecated CAS: 29141-64-8
• Molecular Formula: C18H12 N2 S2
• Molecular Weight: 320.439
• Hs Code.: 29334990
• European Community (EC) Number: 695-308-0
• DSSTox Substance ID: DTXSID1061574
• Nikkaji Number: J7.291E
• Wikidata: Q81989542
• Mol file: 1160-28-7.mol

Synonyms:1160-28-7;Quinoline, 8,8'-dithiobis-;1,2-Di(quinolin-8-yl)disulfane;8,8'-DIQUINOLYL DISULFIDE;8-(quinolin-8-yldisulfanyl)quinoline;8,8'-Quinolyl disulfide;C18H12N2S2;8,8/'-DIQUINOLYL DISULFIDE;Diquinolyldisulfide;8,8'-dithiodiquinoline;8,8 -diquinolyl;8,8-Dithiodiquinoline;Bis(8-quinolyl)disulfide;bis(8-quinolyl)disulphide;bis-(8-quinolyl)disulfide;di(8-quinolinyl) disulfide;8,8'-disulfanediyldiquinoline;BIDD:GT0288;SCHEMBL4037883;8,8-DIQUINOLYLDISULFIDE;DTXSID1061574;8-(8-quinolyldisulfanyl)quinoline;STK025236;AKOS001591919;C18-H12-N2-S2;CS-0329509;FT-0741077;AF-399/40907617

Chemical Property of Quinoline, 8,8'-dithiobis-

Chemical Property:

• Melting Point: 200-208 °C
• Boiling Point: 513.9°Cat760mmHg
• Flash Point: 264.6°C
• PSA: 76.38000
• Density: 1.38g/cm³
• LogP: 5.58240
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 320.04419074
• Heavy Atom Count: 22
• Complexity: 331

Purity/Quality:

98%,99%, ^*data from raw suppliers

8,8'-QUINOLYL DISULFIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 36/37/38-21/22
• Safety Statements: 36/37/39-26-22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C(=C1)SSC3=CC=CC4=C3N=CC=C4)N=CC=C2

Technology Process of Quinoline, 8,8'-dithiobis-

There total 15 articles about Quinoline, 8,8'-dithiobis- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

bis(8-sulfanylquinolinium) hexachloridostannate(IV) → bis(8-quinolinyl)disulfide (1160-28-7)

Guidance literature:

With air; In dimethyl sulfoxide; at 120 ℃; for 8h;

DOI:10.1071/CH19561

Reference yield: 90.0%

divinyltellane (63000-06-6) + quinoline-8-sulfenyl bromide → bis(8-quinolinyl)disulfide (1160-28-7) + divinyltellurium dibromide (86154-47-4)

Guidance literature:

In dichloromethane; at 20 ℃;

DOI:10.3390/molecules26041116

Reference yield: 88.0%

di-tert-butyl-diazodicarboxylate (870-50-8) + sodium quinoline-8-thiolate (2801-16-3) → bis(8-quinolinyl)disulfide (1160-28-7)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 20 ℃; for 6h;

DOI:10.1039/c9gc02824b

upstream raw materials:

quinoline-8-sulfonyl chloride

1,1,1,2,2,3,3-heptafluoro-3-iodo-propane

sodium quinoline-8-thiolate

ethanol

Downstream raw materials:

8-vinylthioquinoline

quinoline-8-sulfonyl chloride

N,N'-bis(diphenyloxyphosphonyl)-8-quinolinesulfinamidine

C₁₇H₁₆N₂O₃S₂

Refernces

• 1、 Liu, Lixia,Luo, Bo,Wang, Chengming. "Synthesis of Symmetrical Thiosulfonates via Cu(OTf)2-Catalyzed Reductive Homocoupling of Arenesulfonyl Chlorides". supporting information. p. 5880 - 5883. Retrieved 2021/11/27.
• 2、 Deka, Rajesh,Sarkar, Arup,Singh, Harkesh B.,Junk, Peter C.,Turner, David R.,Deacon, Glen B.. "Synthesis, Characterization, and Theoretical Studies of cis -Dichloridobis(8-quinolinethiolato)tin(iv) and bis(8-Sulfanylquinolinium) Hexachloridostannate(iv) Derivatives". . p. 1128 - 1137. Retrieved 2020/07/30.