8-Methyl-1-oxaspiro[4.5]decan-2-one

Base Information

Chemical Name:8-Methyl-1-oxaspiro[4.5]decan-2-one
CAS No.:94201-19-1
Molecular Formula:C10H16 O2
Molecular Weight:168.236
Hs Code.:2932209090
European Community (EC) Number:303-602-4
DSSTox Substance ID:DTXSID70888736
Nikkaji Number:J382.422E
Mol file:94201-19-1.mol

Synonyms:8-METHYL-1-OXASPIRO[4.5]DECAN-2-ONE;94201-19-1;EINECS 303-602-4;1-Oxaspiro[4.5]decan-2-one, 8-methyl-;1-Oxaspiro(4.5)decan-2-one, 8-methyl-;8-Methyl-1-oxaspiro(4.5)decan-2-one;SCHEMBL1357905;SCHEMBL3795302;SCHEMBL10988832;SCHEMBL14279104;DTXSID70888736;AKOS006314591

Suppliers and Price of 8-Methyl-1-oxaspiro[4.5]decan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
8-METHYL-1-OXASPIRO[4.5]DECAN-2-ONE 95.00%
5MG
$ 495.76

Total 9 raw suppliers

Chemical Property of 8-Methyl-1-oxaspiro[4.5]decan-2-one

Chemical Property:

Vapor Pressure:0.00872mmHg at 25°C
Boiling Point:266.3°Cat760mmHg
Flash Point:105.6°C
PSA：26.30000
Density:1.04g/cm³
LogP:2.27230
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:168.115029749
Heavy Atom Count:12
Complexity:190

Purity/Quality:

99% ^*data from raw suppliers

8-METHYL-1-OXASPIRO[4.5]DECAN-2-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCC2(CC1)CCC(=O)O2

Technology Process of 8-Methyl-1-oxaspiro[4.5]decan-2-one

There total 4 articles about 8-Methyl-1-oxaspiro[4.5]decan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 3-(1-Hydroxy-4-methyl-cyclohexyl)-propionic acid tert-butyl ester

: 94201-19-1
8-methyl-1-oxaspiro[4.5]-decan-2-one

Guidance literature:: With toluene-4-sulfonic acid; In chloroform; for 24h; Ambient temperature;
DOI:10.1055/s-1998-2108

Reference yield:

: 126036-64-4
8-methyl-1-oxaspiro<4.5>deca-3,7-dien-2-one

: 94201-19-1
8-methyl-1-oxaspiro[4.5]-decan-2-one

Guidance literature:: With hydrogen; palladium on activated charcoal; under 760 - 1520 Torr; Yield given; Ambient temperature;
DOI:10.1021/jo00019a019

Reference yield:

: 38709-71-6
6-methyl-1-oxaspiro[2.5]octane

: 94201-19-1
8-methyl-1-oxaspiro[4.5]-decan-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) LDA, Et₂AlCl / 1.) THF, hexane, -78 deg C, 15 min, 2.) THF, hexane, -35 deg C, 6 h

2: 99 percent / TsOH*H₂O / CHCl₃ / 24 h / Ambient temperature

With diethylaluminium chloride; toluene-4-sulfonic acid; lithium diisopropyl amide; In chloroform;
DOI:10.1055/s-1998-2108