.Alpha.-Canadine methochloride

Base Information

• Chemical Name: .Alpha.-Canadine methochloride
• CAS No.: 47474-49-7
• Molecular Formula: C21H24 N O4
• Molecular Weight: 354.426
• Mol file: 47474-49-7.mol

Synonyms:6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,8,13,13a-tetrahydro-9,10-dimethoxy-7-methyl-, (7S-cis)-;(-)-N-Methylcanadine; (-)-cis-N-Methylcanadine; (-)-a-N-Methylcanadine; N-Methyl-(-)-a-canadinium

Chemical Property of .Alpha.-Canadine methochloride

Chemical Property:

• PSA: 36.92000
• LogP: 3.19140

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of .Alpha.-Canadine methochloride

There total 1 articles about .Alpha.-Canadine methochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

S-Adenosyl-L-methionine (14031-35-7,17176-17-9,29908-03-0,75044-81-4,78548-84-2,79647-17-9,91279-78-6) + canadine (522-97-4,2086-96-6,5096-57-1,29074-38-2) → cis-N-Methylcanadine (47474-49-7)

Guidance literature:

at 30 ℃; for 12h; N-methyltransferase from Eschscholtzia californica, pH 8.0 (glycine puffer); other (S)-tetrahydroprotoberberine alkaloids;

DOI:10.1016/0031-9422(90)85321-6

Reference yield:

cis-N-Methylcanadine (47474-49-7) → allocryptopine (485-91-6,24240-04-8)

Guidance literature:

With oxygen; NADPH; at 30 ℃; for 0.333333h; Yield given; tricine buffer, pH 8.5;

DOI:10.1016/S0040-4039(00)96715-7

upstream raw materials:

S-Adenosyl-L-methionine

canadine

Downstream raw materials:

allocryptopine

Refernces