2-{(E)-1-[4-(dimethylamino)phenyl]methylidene}-1-hydrazinecarboximidamide

Base Information

• Chemical Name: 2-{(E)-1-[4-(dimethylamino)phenyl]methylidene}-1-hydrazinecarboximidamide
• CAS No.: 38407-85-1
• Molecular Formula: C₁₀H₁₅N₅
• Molecular Weight: 205.263
• NSC Number: 66290
• DSSTox Substance ID: DTXSID40876100
• ChEMBL ID: CHEMBL244625
• Mol file: 38407-85-1.mol

Synonyms:CHEMBL244625;NSC 66290;38407-85-1;NSC66290;SCHEMBL7747536;SCHEMBL13381427;SCHEMBL17560834;DTXSID40876100;HMS1578N14;BDBM50371143;NSC-66290;STK066375;AB00373869-02;SR-01000197550;SR-01000197550-1;HYDRAZINECARBOXIMIDAMIDE, 2-[[4-(DIMETHYLAMINO)P;N''-{(E)-[4-(dimethylamino)phenyl]methylidene}carbonohydrazonic diamide

Chemical Property of 2-{(E)-1-[4-(dimethylamino)phenyl]methylidene}-1-hydrazinecarboximidamide

Chemical Property:

• XLogP3: 0.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 205.13274550
• Heavy Atom Count: 15
• Complexity: 234

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=CC=C(C=C1)C=NN=C(N)N
• Isomeric SMILES: CN(C)C1=CC=C(C=C1)/C=N/N=C(N)N

Technology Process of 2-{(E)-1-[4-(dimethylamino)phenyl]methylidene}-1-hydrazinecarboximidamide

There total 3 articles about 2-{(E)-1-[4-(dimethylamino)phenyl]methylidene}-1-hydrazinecarboximidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

hydrazinecarboximidamide hydrochloride (16139-18-7) + 4-dimethylamino-benzaldehyde (100-10-7) → (4-dimethylamino-benzylidenamino)-guanidine (38407-85-1)

Guidance literature:

With hydrogenchloride; In ethanol; for 0.5h; Reflux;

DOI:10.1080/07391102.2016.1176603

Reference yield:

1-aminoguanidine hydrochloride (1937-19-5,16139-18-7) + 4-dimethylamino-benzaldehyde (100-10-7) → (4-dimethylamino-benzylidenamino)-guanidine (38407-85-1) + N,N'''-(4-dimethylamino-benzylidenediamino)-di-guanidine

Guidance literature:

With ethanol; sodium carbonate;

DOI:10.1021/ja01334a039

Reference yield:

ethanol (64-17-5) + 1-aminoguanidine hydrochloride (1937-19-5,16139-18-7) + 4-dimethylamino-benzaldehyde (100-10-7) → (4-dimethylamino-benzylidenamino)-guanidine (38407-85-1) + N,N'''-(4-dimethylamino-benzylidenediamino)-di-guanidine

Guidance literature:

DOI:10.1021/ja01334a039

upstream raw materials:

1-aminoguanidine hydrochloride

4-dimethylamino-benzaldehyde

ethanol

hydrazinecarboximidamide hydrochloride