4-Acetyl-1-methylpiperidin-4-yl benzoate--hydrogen chloride (1/1)

Base Information

Chemical Name:4-Acetyl-1-methylpiperidin-4-yl benzoate--hydrogen chloride (1/1)
CAS No.:98694-59-8
Molecular Formula:C15H20ClNO3
Molecular Weight:297.7772
Hs Code.:
DSSTox Substance ID:DTXSID80913124

Synonyms:98694-59-8;DTXSID80913124;4-Acetyl-1-methylpiperidin-4-yl benzoate--hydrogen chloride (1/1)

Suppliers and Price of 4-Acetyl-1-methylpiperidin-4-yl benzoate--hydrogen chloride (1/1)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Acetyl-1-methylpiperidin-4-yl benzoate--hydrogen chloride (1/1)

Chemical Property:

Vapor Pressure:1.64E-05mmHg at 25°C
Boiling Point:364.8°C at 760 mmHg
Flash Point:174.4°C
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:297.1131712
Heavy Atom Count:20
Complexity:339

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1(CCN(CC1)C)OC(=O)C2=CC=CC=C2.Cl

Technology Process of 4-Acetyl-1-methylpiperidin-4-yl benzoate--hydrogen chloride (1/1)

There total 3 articles about 4-Acetyl-1-methylpiperidin-4-yl benzoate--hydrogen chloride (1/1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.7%

: 20734-45-6
1-Methyl-4-acetylpiperidin-4-ol

: 98-88-4
benzoyl chloride

: 98694-59-8
1-Methyl-4-acetyl-4-benzoyloxy-piperidine

Guidance literature:: With pyridine; at 120 - 125 ℃; for 1h;
DOI:10.1007/BF00833352

Reference yield:

: 1445-73-4
1-Methyl-4-piperidone

: 98694-59-8
1-Methyl-4-acetyl-4-benzoyloxy-piperidine

Guidance literature:: Multi-step reaction with 3 steps

1: 93.8 percent / KOH / diethyl ether; liquid ammonia / 1.) 6 h, 2.) overnight

2: 95.98 percent / HgSO₄, conc. H₂SO₄ / H₂O / 5 h

3: 85.7 percent / pyridine / 1 h / 120 - 125 °C

With pyridine; potassium hydroxide; sulfuric acid; mercury(II) sulfate; In diethyl ether; ammonia; water;
DOI:10.1007/BF00833352

Reference yield:

: 20734-46-7
1-Methyl-4-ethynylpiperidin-4-ol

: 98694-59-8
1-Methyl-4-acetyl-4-benzoyloxy-piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: 95.98 percent / HgSO₄, conc. H₂SO₄ / H₂O / 5 h

2: 85.7 percent / pyridine / 1 h / 120 - 125 °C

With pyridine; sulfuric acid; mercury(II) sulfate; In water;
DOI:10.1007/BF00833352