2,6-Dimethyl-1-nitrosopiperidine

Base Information

• Chemical Name: 2,6-Dimethyl-1-nitrosopiperidine
• CAS No.: 17721-95-8
• Molecular Formula: C7H14 N2 O
• Molecular Weight: 142.201
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID00875699
• Nikkaji Number: J3.451G
• ChEMBL ID: CHEMBL349863
• Mol file: 17721-95-8.mol

Synonyms:2,6-Dimethyl-1-nitrosopiperidine;17721-95-8;nitroso-2,6-dimethylpiperidine;2,6-Dimethyl-N-nitrosopiperidine;2,6-Dimethylnitrosopiperidine;N-Nitroso-2,6-dimethylpiperidine;BRN 0114715;PIPERIDINE, 2,6-DIMETHYL-1-NITROSO-;5-20-04-00188 (Beilstein Handbook Reference);(2S,6R)-2,6-dimethyl-1-nitrosopiperidine;Piperidine, 2,6-dimethyl-1-nitroso-, cis-;CHEMBL349863;SCHEMBL8944270;DTXSID00875699;2,6-Dimethyl-1-nitrosopiperidine #;LS-115122;EN300-21626292

Chemical Property of 2,6-Dimethyl-1-nitrosopiperidine

Chemical Property:

• Vapor Pressure: 0.0629mmHg at 25°C
• Refractive Index: 1.4880 (estimate)
• Boiling Point: 239.2°C at 760 mmHg
• Flash Point: 98.4°C
• PSA: 32.67000
• Density: 1.11g/cm³
• LogP: 1.86860
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 142.110613074
• Heavy Atom Count: 10
• Complexity: 117

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Nitrosamines
• Canonical SMILES: CC1CCCC(N1N=O)C

Technology Process of 2,6-Dimethyl-1-nitrosopiperidine

There total 2 articles about 2,6-Dimethyl-1-nitrosopiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

2.6-dimethylpiperidine (504-03-0) → N-nitroso-2,6-dimethylpiperidine (17721-95-8) + 1-fluoro-2,6-dimethyl-piperidine (24151-83-5)

Guidance literature:

With trifluoroamine oxide; at -10 ℃; for 4h;

DOI:10.1021/ja00162a045

Reference yield:

→ N-nitroso-2,6-dimethylpiperidine (17721-95-8)

Guidance literature:

2,6-Dimethyl-piperidin, wss. Salzsaeure, NaNO2;

DOI:10.1139/v67-417

Reference yield: 97.0%

N-nitroso-2,6-dimethylpiperidine (17721-95-8) → 1-amino-2,6-dimethylpiperidine (39135-39-2)

Guidance literature:

With carbon dioxide; water; ammonium chloride; zinc; at 35 ℃; for 1.5h; under 1500.15 Torr; Autoclave; Green chemistry;

DOI:10.1007/s10593-018-2349-0

upstream raw materials:

2.6-dimethylpiperidine

Downstream raw materials:

2.6-dimethylpiperidine

1-amino-2,6-dimethylpiperidine

Refernces