Phosphonium choline

Base Information

• Chemical Name: Phosphonium choline
• CAS No.: 58887-04-0
• Molecular Formula: C₅H₁₄OP*Cl
• Molecular Weight: 156.592
• DSSTox Substance ID: DTXSID90974382
• Mol file: 58887-04-0.mol

Synonyms:P-choline;phosphonium choline;phosphonium choline iodide

Chemical Property of Phosphonium choline

Chemical Property:

• PSA: 33.82000
• LogP: -2.11030
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 156.0470798
• Heavy Atom Count: 8
• Complexity: 46.5

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[P+](C)(C)CCO.[Cl-]

Technology Process of Phosphonium choline

There total 2 articles about Phosphonium choline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

2-chloro-ethanol (107-07-3) + trimethylphosphane (594-09-2) → (2-hydroxyethyl)trimethylphosphonium chloride (58887-04-0)

Guidance literature:

In toluene; at 100 ℃; for 24h; Inert atmosphere;

DOI:10.1002/cssc.201500612

Reference yield:

→ (2-hydroxyethyl)trimethylphosphonium chloride (58887-04-0)

Guidance literature:

With silver(l) oxide; Behandlung der Loesung der entstandenen Phosphoniumbase mit Salzsaeure;

Reference yield:

(2-hydroxyethyl)trimethylphosphonium chloride (58887-04-0) → C5H13ClP(1+)*Cl(1-)

Guidance literature:

With thionyl chloride; In neat (no solvent); at 0 - 75 ℃; for 2.25h; Schlenk technique; Inert atmosphere; Sealed tube; Glovebox;

DOI:10.1021/acs.biomac.8b00069

upstream raw materials:

2-chloro-ethanol

trimethylphosphane