2-Hydroxydecanedioic acid

Base Information

Chemical Name:2-Hydroxydecanedioic acid
CAS No.:103963-71-9
Molecular Formula:C10H18 O5
Molecular Weight:218.25
Hs Code.:
DSSTox Substance ID:DTXSID40869411
Nikkaji Number:J1.549.240F
Wikidata:Q27161498
Metabolomics Workbench ID:1997
Mol file:103963-71-9.mol

Synonyms:2-hydroxysebacic acid

Suppliers and Price of 2-Hydroxydecanedioic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-HydroxydecanedioicAcid
50mg
$ 865.00

Total 2 raw suppliers

Chemical Property of 2-Hydroxydecanedioic acid

Chemical Property:

Vapor Pressure:4.28E-09mmHg at 25°C
Boiling Point:427.3°Cat760mmHg
Flash Point:226.4°C
PSA：94.83000
Density:1.207g/cm³
LogP:1.24720
Storage Temp.:Refrigerator
Solubility.:Methanol (Slightly)
XLogP3:1.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:218.11542367
Heavy Atom Count:15
Complexity:202

Purity/Quality:

97% ^*data from raw suppliers

2-HydroxydecanedioicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CCCC(C(=O)O)O)CCCC(=O)O
Uses 2-Hydroxydecanedioic Acid is a biomarker to detect?peroxisomal disorders (neonatal adrenoleukodystrophy or Zellweger syndrome) in the urines of children. 2-Hydroxydecanedioic Acid is an oxidation product of sebaic acid (S211410), a urinary metabolite that has been identified as an anti-fatigue biomarker.

Technology Process of 2-Hydroxydecanedioic acid

There total 7 articles about 2-Hydroxydecanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 938447-47-3
(+/-)-2-acetoxydecanedioic acid

: 103963-71-9
(+/-)-2-hydroxydecanedioic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; water; for 12h;
DOI:10.1016/j.tetlet.2007.03.053

Reference yield:

: 938447-45-1
acetic acid 1-vinyldec-9-enyl ester

: 103963-71-9
(+/-)-2-hydroxydecanedioic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / RuCl₃*3H₂O; NaIO₄ / acetonitrile; ethyl acetate; H₂O / 12 h

2: 80 percent / LiOH / tetrahydrofuran; H₂O / 12 h

With ruthenium trichloride; lithium hydroxide; sodium periodate; In tetrahydrofuran; water; ethyl acetate; acetonitrile;
DOI:10.1016/j.tetlet.2007.03.053

Reference yield:

: 81943-76-2
dodeca-1,11-dien-3-ol

: 103963-71-9
(+/-)-2-hydroxydecanedioic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 97 percent / Et₃N / CH₂Cl₂ / 3 h

2: 83 percent / RuCl₃*3H₂O; NaIO₄ / acetonitrile; ethyl acetate; H₂O / 12 h

3: 80 percent / LiOH / tetrahydrofuran; H₂O / 12 h

With ruthenium trichloride; lithium hydroxide; sodium periodate; triethylamine; In tetrahydrofuran; dichloromethane; water; ethyl acetate; acetonitrile;
DOI:10.1016/j.tetlet.2007.03.053