2-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-4-phenylthiazole

Base Information

Chemical Name:2-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-4-phenylthiazole
CAS No.:84125-30-4
Molecular Formula:C₁₆H₁₉NOS
Molecular Weight:273.399
Hs Code.:2934100090
DSSTox Substance ID:DTXSID801004396
Nikkaji Number:J59.609D
Mol file:84125-30-4.mol

Synonyms:BRN 5274758;2-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-4-phenylthiazole;84125-30-4;Thiazole, 2-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-4-phenyl-;2-(2,2-dimethyloxan-4-yl)-4-phenyl-1,3-thiazole;Oprea1_421808;Oprea1_438600;DTXSID801004396;STL324627;AKOS022101786;LS-150985;2-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-4-phenyl-1,3-thiazole

Suppliers and Price of 2-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-4-phenylthiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(2,2-DIMETHYLTETRAHYDRO-2H-PYRAN-4-YL)-4-PHENYLTHIAZOLE 95.00%
5MG
$ 497.86

Total 3 raw suppliers

Chemical Property of 2-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-4-phenylthiazole

Chemical Property:

Vapor Pressure:1.66E-06mmHg at 25°C
Boiling Point:408.4°C at 760 mmHg
Flash Point:200.8°C
PSA：50.36000
Density:1.102g/cm³
LogP:4.48270
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:273.11873540
Heavy Atom Count:19
Complexity:301

Purity/Quality:: 2-(2,2-DIMETHYLTETRAHYDRO-2H-PYRAN-4-YL)-4-PHENYLTHIAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC(CCO1)C2=NC(=CS2)C3=CC=CC=C3)C

Technology Process of 2-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-4-phenylthiazole

There total 3 articles about 2-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-4-phenylthiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.2%

: 84125-26-8
2,2-Dimethyl-tetrahydro-pyran-4-carbothioic acid amide

: 70-11-1
α-bromoacetophenone

: 84125-30-4
2-(2,2-Dimethyl-tetrahydro-pyran-4-yl)-4-phenyl-thiazole

Guidance literature:: In acetone; for 0.166667h;
DOI:10.1007/BF00773094

Reference yield:

: 60549-49-7
2,2-dimethyltetrahydro-2H-pyran-4-carbonyl chloride

: 84125-30-4
2-(2,2-Dimethyl-tetrahydro-pyran-4-yl)-4-phenyl-thiazole

Guidance literature:: Multi-step reaction with 3 steps

1: NH₃ / diethyl ether / 0.5 h / Ambient temperature

2: 43.3 percent / phosphorus pentasulfide / benzene / Heating

3: 78.2 percent / acetone / 0.17 h

With diphosphorus pentasulfide; ammonia; In diethyl ether; acetone; benzene;
DOI:10.1007/BF00773094

Reference yield:

: 60549-50-0
2,2-Dimethyl-tetrahydro-pyran-4-carboxylic acid amide

: 84125-30-4
2-(2,2-Dimethyl-tetrahydro-pyran-4-yl)-4-phenyl-thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 43.3 percent / phosphorus pentasulfide / benzene / Heating

2: 78.2 percent / acetone / 0.17 h

With diphosphorus pentasulfide; In acetone; benzene;
DOI:10.1007/BF00773094