5-Acetamido-1,3,4-thiadiazole-2-sulfonyl chloride

Base Information

Chemical Name:5-Acetamido-1,3,4-thiadiazole-2-sulfonyl chloride
CAS No.:32873-57-7
Molecular Formula:C4H4 Cl N3 O3 S2
Molecular Weight:241.679
Hs Code.:2934999090
DSSTox Substance ID:DTXSID60186536
Wikidata:Q83057852
Mol file:32873-57-7.mol

Synonyms:2-acetamine-5-sulfochloride-1,3,4-thiadiazole;sulfohydrazide

Suppliers and Price of 5-Acetamido-1,3,4-thiadiazole-2-sulfonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(Acetylamino)-1,3,4-thiadiazole-2-sulfonylChloride
1g
$ 1275.00

Azepine
5-Acetamido-1,3,4-thiadiazolyl-2-sulfonylchloride 95
5 g
$ 690.00

American Custom Chemicals Corporation
5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONYL CHLORIDE 95.00%
5MG
$ 496.31

Total 34 raw suppliers

Chemical Property of 5-Acetamido-1,3,4-thiadiazole-2-sulfonyl chloride

Chemical Property:

Melting Point:230 °C
PKA:8.58±0.50(Predicted)
PSA：129.13000
Density:1.788±0.06 g/cm3(Predicted)
LogP:2.15430
Solubility.:Methanol; DMSO; DMF;
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:240.9382610
Heavy Atom Count:13
Complexity:300

Purity/Quality:

99% ^*data from raw suppliers

5-(Acetylamino)-1,3,4-thiadiazole-2-sulfonylChloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=NN=C(S1)S(=O)(=O)Cl
Uses 5-(Acetylamino)-1,3,4-thiadiazole-2-sulfonyl Chloride is an intermediate used in the synthesis of Bis[5-(acetylamino)-1,3,4-thiadiazole-2-sulfonyl]amine (B400160), which is an impurity of Acetazolamide (A161500). Acetazolamide EP Impurity F

Technology Process of 5-Acetamido-1,3,4-thiadiazole-2-sulfonyl chloride

There total 7 articles about 5-Acetamido-1,3,4-thiadiazole-2-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 38583-51-6
N-[5-methylsulfanyl-1,3,4-thiadiazol-2-yl]-acetamide

: 32873-57-7
5-acetamido-1,3,4-thiadiazolyl-2-sulfonyl chloride

Guidance literature:: N-[5-methylsulfanyl-1,3,4-thiadiazol-2-yl]-acetamide; With potassium nitrate; at 6 ℃; for 2.33333h;

With 3-monochlorophenol; lanthanum(III) nitrate; at 4 ℃; for 4.33333h; Temperature;