Pirazolac

Base Information

Chemical Name:Pirazolac
CAS No.:71002-09-0
Molecular Formula:C17H12 Cl F N2 O2
Molecular Weight:330.746
Hs Code.:2933199090
European Community (EC) Number:275-102-3
UNII:FWY2578LP5
DSSTox Substance ID:DTXSID00221233
Nikkaji Number:J19.084E
Wikidata:Q27278246
NCI Thesaurus Code:C66413
ChEMBL ID:CHEMBL249446
Mol file:71002-09-0.mol

Synonyms:4-(4-chlorophenyl)-1-(4-fluorophenyl)pyrazole-3-acetic acid;pirazolac

Suppliers and Price of Pirazolac

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
PIRAZOLAC 95.00%
5MG
$ 499.21

Total 6 raw suppliers

Chemical Property of Pirazolac

Chemical Property:

Vapor Pressure:1.13E-11mmHg at 25°C
Melting Point:148-149°; mp 135-136°
Boiling Point:520.8°C at 760 mmHg
PKA:3.94±0.10(Predicted)
Flash Point:268.8°C
PSA：55.12000
Density:1.36g/cm³
LogP:3.95890
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:330.0571335
Heavy Atom Count:23
Complexity:409

Purity/Quality:

98%Min ^*data from raw suppliers

PIRAZOLAC 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CN(N=C2CC(=O)O)C3=CC=C(C=C3)F)Cl
Uses Antirheumatic.

Technology Process of Pirazolac

There total 11 articles about Pirazolac which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 77442-97-8
2-[4-(4-Chloro-phenyl)-1-(4-fluoro-phenyl)-1H-pyrazol-3-yl]-1-morpholin-4-yl-ethanethione

: 71002-09-0
pirazolac

Guidance literature:: With sodium hydroxide; In water; dimethyl sulfoxide; at 120 ℃; for 8h;

Reference yield: 82.1%

: 81321-74-6
4-(4-Chlorphenyl)-1-(4-fluorphenyl)-pyrazol-3-acetonitril

: 71002-09-0
pirazolac

Guidance literature:: With sodium hydroxide; In water; dimethyl sulfoxide; at 120 ℃; for 3h;

Reference yield:

: 81321-33-7
(E)-N-[2-(4-Chlorophenyl)ethenyl]morpholine

: 71002-09-0
pirazolac

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / CHCl₃ / 1.) 3h, reflux, 2.) room temp.

2: HCl / dioxane; H₂O / 1 h / 100 °C

3: sulphur / 3 h / Heating

4: 90 percent / NaOH / H₂O; dimethylsulfoxide / 8 h / 120 °C

With hydrogenchloride; sodium hydroxide; sulfur; triethylamine; In 1,4-dioxane; chloroform; water; dimethyl sulfoxide;