4-methyl-N-phenylbenzenesulfinamide

Base Information

• Chemical Name: 4-methyl-N-phenylbenzenesulfinamide
• CAS No.: 6873-54-7
• Molecular Formula: C13H13 N O S
• Molecular Weight: 231.318
• Mol file: 6873-54-7.mol

Synonyms:p-Toluenesulfinanilide(6CI,7CI,8CI); N-Phenyl-p-toluenesulfinamide; NSC 243592

Chemical Property of 4-methyl-N-phenylbenzenesulfinamide

Chemical Property:

• Vapor Pressure: 2.82E-06mmHg at 25°C
• Boiling Point: 389.6°Cat760mmHg
• Flash Point: 189.4°C
• Density: 1.25g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-methyl-N-phenylbenzenesulfinamide

There total 25 articles about 4-methyl-N-phenylbenzenesulfinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

iodobenzene (591-50-4) + C13H20N2OS (1310710-45-2) → 1-(p-tolylsulfinyl)aniline (6873-54-7)

Guidance literature:

With potassium carbonate; copper(II) sulfate; 4R-4-hydroxyproline; In dimethyl sulfoxide; at 170 ℃; for 0.166667h; Inert atmosphere; Microwave irradiation;

DOI:10.1055/s-0030-1259682

Reference yield: 84.0%

methyl p-toluene sulfinate (672-78-6) + aniline (62-53-3) → 1-(p-tolylsulfinyl)aniline (6873-54-7)

Guidance literature:

methyl p-toluene sulfinate; With aluminum (III) chloride; In 1,2-dichloro-ethane; at 25 ℃; for 1h; Inert atmosphere;

aniline; In 1,2-dichloro-ethane; at 25 ℃; Inert atmosphere;

DOI:10.1021/jo2006335

Reference yield: 84.0%

aniline (62-53-3) + p-toluenesulfonyl chloride (98-59-9) → 1-(p-tolylsulfinyl)aniline (6873-54-7)

Guidance literature:

With triphenylphosphine; In dichloromethane; at 0 ℃; for 1h;

DOI:10.1002/chem.201002885

upstream raw materials:

4-methylbenzenesulfinyl chloride

(-)-menthol

aniline

p-toluene sulfinic acid

Downstream raw materials:

4-Methyl-2-deuteriobenzenesulfinanilide

N-phenyl-S-(4-methylphenyl)sulfoximidoyl chloride

4-Methyl-2-(phenylthio)benzenesulfinanilide