4-Nitro-1,8-naphthalic anhydride

Base Information

• Chemical Name: 4-Nitro-1,8-naphthalic anhydride
• CAS No.: 6642-29-1
• Molecular Formula: C12H5 N O5
• Molecular Weight: 243.175
• Hs Code.: 2932999099
• European Community (EC) Number: 229-659-4,811-374-7
• NSC Number: 15356
• UNII: 3C7AG4U84M
• DSSTox Substance ID: DTXSID20216641
• Nikkaji Number: J40.513B
• Wikidata: Q83092899
• Mol file: 6642-29-1.mol

Synonyms:4-nitro-1,8-naphthalic anhydride

Chemical Property of 4-Nitro-1,8-naphthalic anhydride

Chemical Property:

• Vapor Pressure: 1.24E-10mmHg at 25°C
• Melting Point: 226-229 °C(lit.)
• Boiling Point: 512.9°C at 760 mmHg
• Flash Point: 264.3°C
• PSA: 89.19000
• Density: 1.637g/cm³
• LogP: 2.58180
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 243.01677226
• Heavy Atom Count: 18
• Complexity: 415

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Nitro-1,8-naphthalic anhydride 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=CC3=C2C(=C1)C(=O)OC3=O)[N+](=O)[O-]

Technology Process of 4-Nitro-1,8-naphthalic anhydride

There total 13 articles about 4-Nitro-1,8-naphthalic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4-nitroacenaphthene (602-87-9) → 4-nitronaphthalic-1,8-anhydride (6642-29-1)

Guidance literature:

With sodium dichromate; acetic acid; at 80 - 95 ℃;

DOI:10.1071/CH15139

Reference yield: 78.0%

2-acetylamino-6-nitrophenalenone (76980-79-5) → 4-nitronaphthalic-1,8-anhydride (6642-29-1)

Guidance literature:

With sodium dichromate; In acetic acid; for 10h; Heating;

Reference yield: 78.0%

5-nitroacenaphthylene (10353-99-8) → 4-nitronaphthalic-1,8-anhydride (6642-29-1)

Guidance literature:

With sodium dichromate; acetic acid; at 22 - 25 ℃; for 5h;

upstream raw materials:

4-nitroacenaphthene

4-nitro-1,8-naphthalenedicarboxylic acid

2-acetylamino-6-nitrophenalenone

5-nitroacenaphthylene

Downstream raw materials:

3-nitro-7H-benzimidazo[2,1-a]benz[de]isoquinolin-7-one

4-nitro-7H-benzimidazo[2,1-a]benz[de]isoquinolin-7-one

N-(2,5-dimethoxy-4-aminophenyl)-4-nitronaphthalene-1,8-dicarboximide

2-butyl-6-(butylamino)-1H-benz(de)isoquinoline-1,3(2H)-dione

Refernces

• 1、 Shi, Wei,Pan, Miaobo,Qiang, Hao,Qiu, Qianqian,Huang, Wenlong,Lin, Haiyan,Qian, Hai,Ge, Liang. "A novel mitochondria-targeting fluorescent probe for hydrogen sulfide in living cells". . p. 167 - 174. Retrieved 2017.
• 2、 Bussotti, Laura,Di Donato, Mariangela,El-Zohry, Ahmed M.,Liu, Dongyi,Matt, Clemens,Mohammed, Omar F.,Taddei, Maria,Wang, Zhijia,Weber, Stefan,Zhao, Jianzhang. "Long-Lived Charge-Transfer State Induced by Spin-Orbit Charge Transfer Intersystem Crossing (SOCT-ISC) in a Compact Spiro Electron Donor/Acceptor Dyad". supporting information. p. 11591 - 11599. Retrieved 2020/05/25.
• 3、 Barbon, Antonio,Chen, Kepeng,Hou, Yuqi,Li, Shujing,Wang, Zhijia,Wu, Huijian,Yaglioglu, Halime Gul,Yildiz, Elif Akhuseyin,Zhang, Xue,Zhao, Jianzhang,Zhao, Yingjie. "Efficient Intersystem Crossing in the Tr?ger's Base Derived From 4-Amino-1,8-naphthalimide and Application as a Potent Photodynamic Therapy Reagent". supporting information. . Retrieved 2020/03/05.