N-(1-Ethyl-3-piperidinyl)-2-methoxy-5-(methylamino)benzamide

Base Information

Chemical Name:N-(1-Ethyl-3-piperidinyl)-2-methoxy-5-(methylamino)benzamide
CAS No.:130260-02-5
Molecular Formula:C16H25 N3 O2
Molecular Weight:291.3886
Hs Code.:
DSSTox Substance ID:DTXSID90926649

Synonyms:130260-02-5;N-(1-Ethyl-3-piperidinyl)-2-methoxy-5-(methylamino)benzamide;BRN 4296038;N-(1-ethylpiperidin-3-yl)-2-methoxy-5-(methylamino)benzamide;Benzamide, N-(1-ethyl-3-piperidinyl)-2-methoxy-5-(methylamino)-;Oprea1_545583;DTXSID90926649;XWHNDBGCEUFEKS-UHFFFAOYSA-N;AKOS005066357;LS-26830;AE-641/30152040;N-(1-Ethylpiperidin-3-yl)-2-methoxy-5-(methylamino)benzene-1-carboximidic acid

Suppliers and Price of N-(1-Ethyl-3-piperidinyl)-2-methoxy-5-(methylamino)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-(1-Ethyl-3-piperidinyl)-2-methoxy-5-(methylamino)benzamide

Chemical Property:

Vapor Pressure:3.19E-08mmHg at 25°C
Boiling Point:448.1°C at 760 mmHg
Flash Point:224.8°C
Density:1.12g/cm³
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:291.19467705
Heavy Atom Count:21
Complexity:338

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1CCCC(C1)NC(=O)C2=C(C=CC(=C2)NC)OC

Technology Process of N-(1-Ethyl-3-piperidinyl)-2-methoxy-5-(methylamino)benzamide

There total 6 articles about N-(1-Ethyl-3-piperidinyl)-2-methoxy-5-(methylamino)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 130260-00-3
N-(1-ethyl-3-piperidinyl)-2-methoxy-5-(N-methyl-N-(4-toluenesulfonyl)amino)benzamide

: 130260-02-5
N-(1-ethyl-3-piperidinyl)-2-methoxy-5-(methylamino)benzamide

Guidance literature:: With sulfuric acid; In diethyl ether; at 40 - 70 ℃; for 3h;

Reference yield:

: 6789-94-2
1-ethylpiperidin-3-amine

: 130260-02-5
N-(1-ethyl-3-piperidinyl)-2-methoxy-5-(methylamino)benzamide

Guidance literature:: Multi-step reaction with 5 steps

1: 81 percent / CHCl₃ / 1.5 h / Heating

2: 82 percent / N₂H₄*H₂O, Raney Ni / ethanol / 1.5 h / 60 °C

3: 94 percent / NaHCO₃ / CH₂Cl₂

4: 67 percent / tetrabutylamonium hydrogen sulfate, KOH / CH₂Cl₂; H₂O / 1 h / Ambient temperature

5: 83 percent / 90percent H₂SO₄ / diethyl ether / 3 h / 40 - 70 °C

With potassium hydroxide; sulfuric acid; tetra(n-butyl)ammonium hydrogensulfate; nickel; sodium hydrogencarbonate; hydrazine hydrate; In diethyl ether; ethanol; dichloromethane; chloroform; water;

Reference yield:

: 90763-46-5
2-methoxy-5-nitrobenzoyl chloride

: 130260-02-5
N-(1-ethyl-3-piperidinyl)-2-methoxy-5-(methylamino)benzamide

Guidance literature:: Multi-step reaction with 5 steps

1: 81 percent / CHCl₃ / 1.5 h / Heating

2: 82 percent / N₂H₄*H₂O, Raney Ni / ethanol / 1.5 h / 60 °C

3: 94 percent / NaHCO₃ / CH₂Cl₂

4: 67 percent / tetrabutylamonium hydrogen sulfate, KOH / CH₂Cl₂; H₂O / 1 h / Ambient temperature

5: 83 percent / 90percent H₂SO₄ / diethyl ether / 3 h / 40 - 70 °C

With potassium hydroxide; sulfuric acid; tetra(n-butyl)ammonium hydrogensulfate; nickel; sodium hydrogencarbonate; hydrazine hydrate; In diethyl ether; ethanol; dichloromethane; chloroform; water;