5,6-dimethoxyindeno[1,2,3-ij]isoquinolin-9(1H)-one

Base Information

Chemical Name:5,6-dimethoxyindeno[1,2,3-ij]isoquinolin-9(1H)-one
CAS No.:78416-88-3
Molecular Formula:C₁₇H₁₃NO₃
Molecular Weight:279.295
Hs Code.:

Synonyms:

Suppliers and Price of 5,6-dimethoxyindeno[1,2,3-ij]isoquinolin-9(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5,6-dimethoxyindeno[1,2,3-ij]isoquinolin-9(1H)-one

Chemical Property:

Vapor Pressure:1.47E-21mmHg at 25°C
Boiling Point:736.5°C at 760 mmHg
Flash Point:399.3°C
Density:1.37g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5,6-dimethoxyindeno[1,2,3-ij]isoquinolin-9(1H)-one

There total 14 articles about 5,6-dimethoxyindeno[1,2,3-ij]isoquinolin-9(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: C₂₀H₁₉NO₃

: 78416-88-3
telitoxine

Guidance literature:: With aluminum (III) chloride; In dichloromethane; at 20 ℃; for 0.5h;
DOI:10.1002/ejoc.201500866

Reference yield:

: 54291-90-6
5-bromo-3,4-dimethoxy-1-(2-nitrovinyl)benzene

: 78416-88-3
telitoxine

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 4 h / Inert atmosphere; Reflux

2.1: sodium carbonate / dichloromethane / 40 h / 20 °C

3.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / water; toluene; ethanol / 24 h / Inert atmosphere; Reflux

4.1: acetic acid; hydrogen bromide / 1,4-dioxane / 2 h / 20 °C

4.2: 24 h / 20 °C

5.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 24 h / 100 °C

6.1: aluminum (III) chloride / dichloromethane / 0.5 h / 20 °C

With aluminum (III) chloride; sodium tetrahydroborate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; boron trifluoride diethyl etherate; hydrogen bromide; sodium carbonate; potassium carbonate; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; 3.1: |Suzuki Coupling;
DOI:10.1002/ejoc.201500866

Reference yield:

: 56139-04-9
2-(3-bromo-4,5-dimethoxyphenyl)ethanamine

: 78416-88-3
telitoxine

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium carbonate / dichloromethane / 40 h / 20 °C

2.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / water; toluene; ethanol / 24 h / Inert atmosphere; Reflux

3.1: acetic acid; hydrogen bromide / 1,4-dioxane / 2 h / 20 °C

3.2: 24 h / 20 °C

4.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 24 h / 100 °C

5.1: aluminum (III) chloride / dichloromethane / 0.5 h / 20 °C

With aluminum (III) chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrogen bromide; sodium carbonate; potassium carbonate; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; In 1,4-dioxane; ethanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; 2.1: |Suzuki Coupling;
DOI:10.1002/ejoc.201500866