Tetrahydro-1H,3H-pyrrolo(1,2-c)oxazole-1,3-dione

Base Information

Chemical Name:Tetrahydro-1H,3H-pyrrolo(1,2-c)oxazole-1,3-dione
CAS No.:5626-64-2
Molecular Formula:C6H7 N O3
Molecular Weight:141.126
Hs Code.:
European Community (EC) Number:227-066-5,691-846-5
DSSTox Substance ID:DTXSID10971691
Nikkaji Number:J225.065I
Mol file:5626-64-2.mol

Synonyms:5626-64-2;EINECS 227-066-5;Tetrahydro-1H,3H-pyrrolo(1,2-c)oxazole-1,3-dione;TETRAHYDRO-1H,3H-PYRROLO[1,2-C]OXAZOLE-1,3-DIONE;(7AS)-TETRAHYDRO-1H,3H-PYRROLO[1,2-C]OXAZOLE-1,3-DIONE;45736-33-2;SCHEMBL8844037;JNWNBXNPBSVNMU-UHFFFAOYSA-;DTXSID10971691;3,4-Propanooxazole-2,5(3H,4H)-dione;1H,3H-Pyrrolo(1,2-c)oxazole-1,3-dione, tetrahydro-;Tetrahydro-1H,3H-pyrrolo[1,2-c][1,3]oxazole-1,3-dione

Suppliers and Price of Tetrahydro-1H,3H-pyrrolo(1,2-c)oxazole-1,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Tetrahydro-1H,3H-pyrrolo(1,2-c)oxazole-1,3-dione

Chemical Property:

Vapor Pressure:0.326mmHg at 25°C
Boiling Point:200.4°Cat760mmHg
Flash Point:75°C
PSA：46.61000
Density:1.43g/cm³
LogP:0.06550
XLogP3:0.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:141.042593085
Heavy Atom Count:10
Complexity:201

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2C(=O)OC(=O)N2C1

Technology Process of Tetrahydro-1H,3H-pyrrolo(1,2-c)oxazole-1,3-dione

There total 4 articles about Tetrahydro-1H,3H-pyrrolo(1,2-c)oxazole-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 32315-10-9
bis(trichloromethyl) carbonate

: 609-36-9,25191-13-3,37159-97-0,4305-67-3,4607-28-7
rac-Pro-OH

: (S)-1-Chlorocarbonyl-pyrrolidine-2-carboxylic acid

: 5626-64-2
DL-Pro-NCA

Guidance literature:: In tetrahydrofuran; at 50 ℃; for 1h;
DOI:10.1021/ol0622965

Reference yield: 93.0%

: 32315-10-9
bis(trichloromethyl) carbonate

: 609-36-9,25191-13-3,37159-97-0,4305-67-3,4607-28-7
rac-Pro-OH

: 5626-64-2
DL-Pro-NCA

Guidance literature:: bis(trichloromethyl) carbonate; rac-Pro-OH; In tetrahydrofuran; at 50 ℃; for 1h;

With (N,N-diethylaminomethyl)-functionalyzed polystyrene resin; In tetrahydrofuran; at 20 ℃; for 3h;
DOI:10.1021/ol0622965

Reference yield: 35.0%

: 32315-10-9
bis(trichloromethyl) carbonate

: 609-36-9,25191-13-3,37159-97-0,4305-67-3,4607-28-7
rac-Pro-OH

: (S)-1-Chlorocarbonyl-pyrrolidine-2-carboxylic acid

: 5626-64-2
DL-Pro-NCA

: 19943-27-2
rac-octahydrodipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione

Guidance literature:: bis(trichloromethyl) carbonate; rac-Pro-OH; In tetrahydrofuran; at 50 ℃; for 1h;

With triethylamine; In tetrahydrofuran; at 20 ℃; for 3h; Title compound not separated from byproducts;
DOI:10.1021/ol0622965