SODIUM BROMOACETATE

Base Information

• Chemical Name: SODIUM BROMOACETATE
• CAS No.: 1068-52-6
• Molecular Formula: C2H3BrO2.Na
• Molecular Weight: 160.93
• Hs Code.: 2915900090
• Mol file: 1068-52-6.mol

Synonyms:Sodium bromoacetate;Sodium monobromoacetate;Bromoaceticacid sodium salt;CID14038;LS-11183;

Chemical Property of SODIUM BROMOACETATE

Chemical Property:

• Vapor Pressure: 0.0929mmHg at 25°C
• Melting Point: >300 °C
• Boiling Point: 207 °C at 760 mmHg
• Flash Point: 79 °C
• PSA: 40.13000
• LogP: -0.86880
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility.: Soluble in water.

Purity/Quality:

98%,99%, ^*data from raw suppliers

Sodium2-bromoacetate 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R25:Toxic if swallowed.; R36/37/38:Irritating to eyes, respiratory system and skin.
• Hazard Codes: R25:Toxic if swallowed.; R36/37/38:Irritating to eyes, respiratory system and skin.
• Statements: 25-36/37/38
• Safety Statements: 22-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Uses: It is an important raw material and intermediate used in organic synthesis, agrochemical, pharmaceutical and dyestuff field.

Technology Process of SODIUM BROMOACETATE

There total 2 articles about SODIUM BROMOACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

bromoacetic anhydride (13094-51-4) + hyaluronan → HABA + sodium 2-bromoacetate (1068-52-6) + sodium glycolate (25289-18-3,105938-46-3,2836-32-0)

Guidance literature:

With sodium hydroxide; In water; at 4 ℃; for 24h; pH=9.0;

Reference yield:

bromoacetic acid (79-08-3) → sodium 2-bromoacetate (1068-52-6)

Guidance literature:

With sodium hydride; In tetrahydrofuran;

Reference yield: 93.0%

(1R,4R,5S,6R)-6-(4-methoxybenzyloxy)-4-hydroxy-2,8-dioxa-bicyclo[3.3.0]octane (1292810-73-1) + sodium 2-bromoacetate (1068-52-6) → 2-{(1S,4R,5R,6R)-6-(4-methoxybenzyloxy)-2,8-dioxa-bicyclo[3.3.0]octane-4-yloxy}acetic acid

Guidance literature:

(1R,4R,5S,6R)-6-(4-methoxybenzyloxy)-4-hydroxy-2,8-dioxa-bicyclo[3.3.0]octane; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃;

sodium 2-bromoacetate; In tetrahydrofuran; mineral oil; at 80 ℃;

DOI:10.1021/acs.jmedchem.5b00358

upstream raw materials:

bromoacetic anhydride

bromoacetic acid

Downstream raw materials:

(N',N'-diphenyl-hydrazino)-acetic acid

bromoacetic anhydride

glycolide

4-nitrobenzyl bromoacetate

Refernces

• 1、 -. "Compounds derived from menthol and use as refreshing agent". Page column 6. . Retrieved 2008/06/13.