Methyl 4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate

Base Information

Chemical Name:Methyl 4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate
CAS No.:30341-92-5
Molecular Formula:C16H18 N2 O2
Molecular Weight:270.331
Hs Code.:
European Community (EC) Number:805-980-0
Mol file:30341-92-5.mol

Synonyms:6-nor-9,10-dihydrolysergic acid methyl ester;methyl 6-nor-9,10-dihydrolysergate

Suppliers and Price of Methyl 4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ERGOLINE-8-CARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 502.15

Total 23 raw suppliers

Chemical Property of Methyl 4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate

Chemical Property:

Vapor Pressure:5.33E-09mmHg at 25°C
Boiling Point:469.8°Cat760mmHg
PKA:17.40±0.40(Predicted)
Flash Point:237.9°C
PSA：54.12000
Density:1.248g/cm³
LogP:2.28750
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:270.136827821
Heavy Atom Count:20
Complexity:400

Purity/Quality:

99%, ^*data from raw suppliers

ERGOLINE-8-CARBOXYLIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1CC2C(CC3=CNC4=CC=CC2=C34)NC1

Technology Process of Methyl 4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate

There total 20 articles about Methyl 4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 80993-64-2
9-methyl 7-(2,2,2-trichloroethyl) (6aR,9R,10aR)-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxylate

: 30341-92-5
methyl (6aR,9R,10aR)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate

Guidance literature:: With acetic acid; zinc; for 60h; Heating;
DOI:10.1002/jps.2600701207

Reference yield:

: 51260-62-9
D-6-cyano-8β-methoxycarbonylergoline

: 30341-92-5
methyl (6aR,9R,10aR)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate

Guidance literature:: With hydrogen; W-7 Raney Ni; In N,N-dimethyl-formamide;
DOI:10.1248/cpb.42.1463

Reference yield:

: 3006-19-7,5143-94-2,35470-53-2,77842-02-5,87247-99-2,96648-31-6,96648-32-7
9,10-dihydrolysergic acid methyl ester

: 30341-92-5
methyl (6aR,9R,10aR)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: CH₂Cl₂

2: H₂ / W-7 Raney Ni / dimethylformamide

With hydrogen; W-7 Raney Ni; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.42.1463