CP 61405

Base Information

Chemical Name:CP 61405
CAS No.:99623-84-4
Molecular Formula:
Molecular Weight:
Hs Code.:

Synonyms:

Suppliers and Price of CP 61405

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of CP 61405

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of CP 61405

There total 34 articles about CP 61405 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 144604-79-5
routiennocin methyl ester

: 99623-84-4
Routiennocin

Guidance literature:: With lithium hydroxide; water; In tetrahydrofuran; for 12h; Ambient temperature;
DOI:10.1016/S0040-4020(01)80467-1

Reference yield:

: 91285-62-0,111322-01-1,119239-98-4
(S)-1-(benzyloxy)-3-hydroxyhex-5-ene

: 99623-84-4
Routiennocin

Guidance literature:: Multi-step reaction with 18 steps

1: 1.) 9-borabicyclo<3.3.1>nonane, 2.) 3N aq. NaOH, 30percent H₂O₂ / 1.) THF, 65 deg C, 3 h, 2.) 1 h, r.t.

2: 97 percent / camphorsulphonic acid / CH₂Cl₂ / 1 h / Ambient temperature

3: 80 percent / H₂ / 10percent Pd/C / ethanol / 12 h / Ambient temperature

4: 88 percent / camphorsulphonic acid, CuSO₄ / acetone / 10 h / Ambient temperature

5: Et₃N / CH₂Cl₂ / 1 h

6: NaI / acetone / 3 h / 40 °C

8: 76 percent / NaH / paraffin; tetrahydrofuran / 3 h / Ambient temperature

9: 71 percent / n-Bu₄NF / tetrahydrofuran / 8 h / Ambient temperature

10: 1.) 4-methylmorpholine-N-oxide (NMO), 4 Angstroem molecular sieves, 2.) tetra-n-propylammonium perruthenate (TPAP) / 1.) CH₂Cl₂, 10 min, r.t., 2.) 1 h

11: 1.) BuLi / 1.) hexane, DME, a) -10 deg C, 20 min, b) 0 deg C, 0.5 h, 2.) THF, DME, a) -10 deg C, 0.5 h, b) -10 deg C to r.t., 2 h

12: 1.) 4-methylmorpholine-N-oxide (NMO), 4 Angstroem molecular sieves, 2.) tetra-n-propylammonium perruthenate (TPAP) / 1.) CH₃CN, 10 min, r.t., 2.) 3 h

13: 86 percent / H₂ / 10percent Pd/C / ethanol / 5 h / Ambient temperature

14: 84 percent / CrO₃, conc. H₂SO₄ / H₂O; acetone / 1 h / -25 - -5 °C

15: 1.) ClCO₂Et, Et₃N / 1.) CH₂Cl₂, -10 deg C, 30 min, 2.) THF, a) -10 deg C, 1 h, b) 16 h, r.t.

16: 71 percent / ethyl polyphosphate (PPE) / CHCl₃ / 1 h / 60 °C

17: 88 percent / TBAF / tetrahydrofuran / a) 0 deg C, 10 min, b) 4 h, r.t.

18: 93 percent / H₂O, LiOH*H₂O / tetrahydrofuran / 12 h / Ambient temperature

With chromium(VI) oxide; lithium hydroxide; sodium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; n-butyllithium; tetrapropylammonium perruthennate; ethyl phosphate; 4 A molecular sieve; ethyl polyphosphate (ppe); sulfuric acid; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; water; hydrogen; dihydrogen peroxide; chloroformic acid ethyl ester; sodium hydride; copper(II) sulfate; 4-methylmorpholine N-oxide; triethylamine; sodium iodide; palladium on activated charcoal; In tetrahydrofuran; ethanol; dichloromethane; chloroform; water; acetone; paraffin;
DOI:10.1016/S0040-4020(01)80467-1

Reference yield:

: (S)-7-Benzyloxy-5-hydroxy-heptanoic acid methyl ester

: 99623-84-4
Routiennocin

Guidance literature:: Multi-step reaction with 10 steps

2: 1.) 4-methylmorpholine-N-oxide (NMO), 4 Angstroem molecular sieves, 2.) tetra-n-propylammonium perruthenate (TPAP) / 1.) CH₂Cl₂, 10 min, r.t., 2.) 1 h

3: 1.) BuLi / 1.) hexane, DME, a) -10 deg C, 20 min, b) 0 deg C, 0.5 h, 2.) THF, DME, a) -10 deg C, 0.5 h, b) -10 deg C to r.t., 2 h

4: 1.) 4-methylmorpholine-N-oxide (NMO), 4 Angstroem molecular sieves, 2.) tetra-n-propylammonium perruthenate (TPAP) / 1.) CH₃CN, 10 min, r.t., 2.) 3 h

5: 86 percent / H₂ / 10percent Pd/C / ethanol / 5 h / Ambient temperature

6: 84 percent / CrO₃, conc. H₂SO₄ / H₂O; acetone / 1 h / -25 - -5 °C

7: 1.) ClCO₂Et, Et₃N / 1.) CH₂Cl₂, -10 deg C, 30 min, 2.) THF, a) -10 deg C, 1 h, b) 16 h, r.t.

8: 71 percent / ethyl polyphosphate (PPE) / CHCl₃ / 1 h / 60 °C

9: 88 percent / TBAF / tetrahydrofuran / a) 0 deg C, 10 min, b) 4 h, r.t.

10: 93 percent / H₂O, LiOH*H₂O / tetrahydrofuran / 12 h / Ambient temperature

With chromium(VI) oxide; lithium hydroxide; n-butyllithium; tetrapropylammonium perruthennate; ethyl phosphate; 4 A molecular sieve; ethyl polyphosphate (ppe); sulfuric acid; tetrabutyl ammonium fluoride; water; hydrogen; chloroformic acid ethyl ester; 4-methylmorpholine N-oxide; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol; chloroform; water; acetone;
DOI:10.1016/S0040-4020(01)80467-1