Ethyl N-(2-ethoxy-2-oxoethyl)-N-methylglycinate

Base Information

• Chemical Name: Ethyl N-(2-ethoxy-2-oxoethyl)-N-methylglycinate
• CAS No.: 5412-66-8
• Molecular Formula: C9H17 N O4
• Molecular Weight: 203.238
• Hs Code.: 2922499990
• European Community (EC) Number: 226-496-0
• NSC Number: 6318
• UNII: 2YYB3A4Y5T
• DSSTox Substance ID: DTXSID80202464
• Nikkaji Number: J217.984I
• Wikidata: Q83075735
• Mol file: 5412-66-8.mol

Synonyms:5412-66-8;DIETHYL N-METHYLIMINODIACETATE;Ethyl N-(2-ethoxy-2-oxoethyl)-N-methylglycinate;ethyl 2-[(2-ethoxy-2-oxoethyl)-methylamino]acetate;2YYB3A4Y5T;NSC-6318;EINECS 226-496-0;N-(2-Ethoxy-2-oxoethyl)-N-methylglycine ethyl ester;NSC6318;Diethyl 2,2'-(methylazanediyl)diacetate;UNII-2YYB3A4Y5T;ethyl 2-[(2-ethoxy-2-oxoethyl)(methyl)amino]acetate;SCHEMBL12589581;DTXSID80202464;NSC 6318;MFCD00026894;AKOS011289218;DIETHYL (METHYLIMINO)-DIACETATE;AS-10584;CS-0367709;D87721;N-[(Ethoxycarbonyl)methyl]-N-methylglycine ethyl ester;Glycine, N-(2-ethoxy-2-oxoethyl)-N-methyl-, ethyl ester;diethyl 2,2'-(methylazanediyl)diacetate ethyl N-(2-ethoxy-2-oxoethyl)-N-methylglycinate

Chemical Property of Ethyl N-(2-ethoxy-2-oxoethyl)-N-methylglycinate

Chemical Property:

• Vapor Pressure: 0.0184mmHg at 25°C
• Boiling Point: 253.3°Cat760mmHg
• Flash Point: 107°C
• PSA: 55.84000
• Density: 1.062g/cm³
• LogP: 0.04440
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 8
• Exact Mass: 203.11575802
• Heavy Atom Count: 14
• Complexity: 173

Purity/Quality:

DIETHYL (METHYLIMINO)-DIACETATE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)CN(C)CC(=O)OCC

Technology Process of Ethyl N-(2-ethoxy-2-oxoethyl)-N-methylglycinate

There total 4 articles about Ethyl N-(2-ethoxy-2-oxoethyl)-N-methylglycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

ethanol (64-17-5) + N-methyliminodiacetic acid (4408-64-4) → diethyl 2,2'-(methylimino)diacetate (5412-66-8)

Guidance literature:

With hydrogenchloride; In water; at 0 - 70 ℃; for 12h; Inert atmosphere;

Reference yield:

Sarcosine ethyl ester (13200-60-7) → diethyl 2,2'-(methylimino)diacetate (5412-66-8)

Guidance literature:

DOI:10.1021/ja01330a065

Reference yield:

→ diethyl 2,2'-(methylimino)diacetate (5412-66-8)

Guidance literature:

N-Methyliminodiessigsaeure, Ethanol;

upstream raw materials:

ethanol

N-methyliminodiacetic acid

Sarcosine ethyl ester

C₆₉H₁₇NO₄

Downstream raw materials:

1-(3,4-dimethoxy-phenethyl)-4-methyl-piperazine-2,6-dione

methylimino-di-acetic acid bis-(3,4-dimethoxy-phenethylamide)

1-benzyl-4-methyl-piperazine-2,6-dione

N-(6,7-dimethoxy-3,4-dihydro-[1]isoquinolylmethyl)-N-methyl-glycine-(3,4-dimethoxy-phenethylamide)