Moxaverine

Base Information

Chemical Name:Moxaverine
CAS No.:10539-19-2
Molecular Formula:C20H21 N O2
Molecular Weight:307.392
Hs Code.:2933499090
European Community (EC) Number:234-117-5
UNII:P3P08Y1XJ4
DSSTox Substance ID:DTXSID6057613
Nikkaji Number:J10.451E
Wikipedia:Moxaverine
Wikidata:Q425881
NCI Thesaurus Code:C66209
Metabolomics Workbench ID:153274
ChEMBL ID:CHEMBL2105060
Mol file:10539-19-2.mol

Synonyms:Certonal;Eupaverin;Kollateral;moxaverine;moxaverine hydrochloride;moxaverine sulfate (1:1)

Suppliers and Price of Moxaverine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-Benzyl-3-ethyl-6,7-dimethoxyisoquinoline hydrochloride 97%
1g
$ 1039.00

Crysdot
1-Benzyl-3-ethyl-6,7-dimethoxyisoquinoline 97%
1g
$ 720.00

Chemenu
1-Benzyl-3-ethyl-6,7-dimethoxyisoquinoline 97%
1g
$ 680.00

Atlantic Research Chemicals
1-Benzyl-3-ethyl-6,7-dimethoxyisoquinoline 95%
250mgs:
$ 247.42

American Custom Chemicals Corporation
1-BENZYL-3-ETHYL-6,7-DIMETHOXYISOQUINOLINE 95.00%
5MG
$ 499.51

AK Scientific
1-Benzyl-3-ethyl-6,7-dimethoxyisoquinoline
1g
$ 1562.00

AK Scientific
1-Benzyl-3-ethyl-6,7-dimethoxyisoquinoline
500mg
$ 927.00

Total 10 raw suppliers

Chemical Property of Moxaverine

Chemical Property:

Vapor Pressure:1.44E-07mmHg at 25°C
Melting Point:71-72.5°
Boiling Point:441.2°Cat760mmHg
PKA:7.12±0.50(Predicted)
Flash Point:158.7°C
PSA：31.35000
Density:1.109g/cm³
LogP:4.40520
XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:307.157228913
Heavy Atom Count:23
Complexity:356

Purity/Quality:

99%, ^*data from raw suppliers

1-Benzyl-3-ethyl-6,7-dimethoxyisoquinoline hydrochloride 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=NC(=C2C=C(C(=CC2=C1)OC)OC)CC3=CC=CC=C3
Recent ClinicalTrials:A Randomized, Placebo-controlled Study Investigating the Effects of Moxaverine on Ocular Blood Flow After Oral Administration in Healthy Subjects
Recent EU Clinical Trials:An open study comparing the effects of moxaverine on ocular blood flow in patients with age- related macular degeneration, primary open angle glaucoma and healthy control subjects

Technology Process of Moxaverine

There total 8 articles about Moxaverine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: C₁₄H₁₉NO₄

: 536-74-3
phenylacetylene

: 10539-19-2
Moxaverine

Guidance literature:: With copper diacetate; potassium carbonate; 2,6-bis(4,5-dihydrooxazol-2-yl)pyridine; In 1,2-dichloro-ethane; at 100 - 110 ℃; for 36h; Sealed tube; Inert atmosphere;
DOI:10.1002/anie.202110901

Reference yield: 83.0%

: 1-(3,4-dimethoxyphenyl)-N-(phenylethynyl)butan-2-imine

: 10539-19-2
Moxaverine

Guidance literature:: With copper diacetate; potassium carbonate; 2,6-bis(4,5-dihydrooxazol-2-yl)pyridine; In 1,2-dichloro-ethane; at 110 ℃; for 12h; Sealed tube; Inert atmosphere;
DOI:10.1002/anie.202110901

Reference yield: 65.0%

: 1-(1-benzyl-6,7-dimethoxyisoquinolin-3-yl)ethan-1-one

: 10539-19-2
Moxaverine

Guidance literature:: 1-(1-benzyl-6,7-dimethoxyisoquinolin-3-yl)ethan-1-one; With toluene-4-sulfonic acid hydrazide; In methanol; for 12h; Heating;

With diisobutylaluminium hydride; In hexane; dichloromethane; at 20 ℃; for 1h;
DOI:10.1039/c6ob00942e