ZOMEPIRAC SODIUM SALT

Base Information

• Chemical Name: ZOMEPIRAC SODIUM SALT
• CAS No.: 64092-48-4
• Molecular Formula: C15H14 Cl N O3 . Na
• Molecular Weight: 313.716
• Hs Code.: 2933990090
• Mol file: 64092-48-4.mol

Synonyms:1H-Pyrrole-2-aceticacid, 5-(4-chlorobenzoyl)-1,4-dimethyl-, sodium salt (9CI);McN 2783-21-98;Sodium zomepirac;Zomax;Zomepirac sodium;Zomepirac sodium salt;

Chemical Property of ZOMEPIRAC SODIUM SALT

Chemical Property:

• Vapor Pressure: 1.15E-09mmHg at 25°C
• Boiling Point: 470.8°C at 760 mmHg
• Flash Point: 238.5°C
• PSA: 62.13000
• LogP: 1.51030

Purity/Quality:

99% ^*data from raw suppliers

Zomepirac sodium salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 23/24/25
• Safety Statements: 22-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Zomepirac is an analgesic, anti-inflammatory drug. antibacterial

Technology Process of ZOMEPIRAC SODIUM SALT

There total 1 articles about ZOMEPIRAC SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ sodium [5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]-acetate (64092-48-4)

Guidance literature:

Reference yield: 83.0%

3,5-dimethyl-1H-pyrazole (67-51-6) + sodium [5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]-acetate (64092-48-4) → 2-(5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl)-1-(3,5-dimethyl-1H-pyrazol-1-yl)ethan-1-one

Guidance literature:

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/acs.orglett.7b01293

Reference yield: 80.0%

chloroacetonitrile (107-14-2) + sodium [5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]-acetate (64092-48-4) → cyanomethyl [5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]-acetate

Guidance literature:

In dichloromethane; dimethyl sulfoxide;

Refernces