Propanedioic acid, [(2-chlorophenyl)methylene]-, diethyl ester

Base Information

Chemical Name:Propanedioic acid, [(2-chlorophenyl)methylene]-, diethyl ester
CAS No.:6768-20-3
Molecular Formula:C14H15ClO4
Molecular Weight:282.724
Hs Code.:2917399090
NSC Number:168418
DSSTox Substance ID:DTXSID60304935
Nikkaji Number:J109.832B
ChEMBL ID:CHEMBL1991082
Mol file:6768-20-3.mol

Synonyms:6768-20-3;Propanedioic acid, [(2-chlorophenyl)methylene]-, diethyl ester;NSC168418;Malonic acid, (o-chlorobenzylidene)-, diethyl ester;CHEMBL1991082;SCHEMBL11781170;DTXSID60304935;NSC-168418;NCI60_001336;Diethyl 2-(2-chlorobenzylidene)malonate #;[(2-Chlorophenyl)methylene]propanedioic acid, diethyl ester

Suppliers and Price of Propanedioic acid, [(2-chlorophenyl)methylene]-, diethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Propanedioic acid, [(2-chlorophenyl)methylene]-, diethyl ester

Chemical Property:

PSA：52.60000
LogP:2.84960
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:282.0658866
Heavy Atom Count:19
Complexity:331

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(=CC1=CC=CC=C1Cl)C(=O)OCC

Technology Process of Propanedioic acid, [(2-chlorophenyl)methylene]-, diethyl ester

There total 5 articles about Propanedioic acid, [(2-chlorophenyl)methylene]-, diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 631-22-1
diethyl dibromomalonate

: 89-98-5
2-chloro-benzaldehyde

: 6768-20-3
diethyl 2-chlorobenzylidene malonate

Guidance literature:: With dibutyl telluride; In tetrahydrofuran; at 50 ℃;
DOI:10.1080/00397919108019792

Reference yield: 91.0%

: 89-98-5
2-chloro-benzaldehyde

: 105-53-3
diethyl malonate

: 6768-20-3
diethyl 2-chlorobenzylidene malonate

Guidance literature:: With ytterbium(III) triflate; at 80 - 85 ℃; for 7h; neat (no solvent);
DOI:10.5012/jkcs.2011.55.6.1000

Reference yield: 65.0%

: 105-53-3
diethyl malonate

: 89-97-4
2-CHLOROBENZYLAMINE

: 6768-20-3
diethyl 2-chlorobenzylidene malonate

Guidance literature:: 2-CHLOROBENZYLAMINE; With fluorenone imine; In toluene; at 20 ℃; for 1h;

diethyl malonate; In toluene; for 48h; Reflux; Inert atmosphere;
DOI:10.1039/c9ob02163a