3,5-Dibromoaniline

Base Information

• Chemical Name: 3,5-Dibromoaniline
• CAS No.: 626-40-4
• Molecular Formula: C6H5 Br2 N
• Molecular Weight: 250.92
• Hs Code.: 2921420090
• Mol file: 626-40-4.mol

Synonyms:Aniline,3,5-dibromo- (6CI,7CI,8CI); 3,5-Dibromoaniline; 3,5-Dibromobenzenamine; NSC6216

Chemical Property of 3,5-Dibromoaniline

Chemical Property:

• Vapor Pressure: 0.0014mmHg at 25°C
• Melting Point: 56.5oC
• Refractive Index: 1.6300 (estimate)
• Boiling Point: 296.8oC at 760 mmHg
• PKA: 2.45±0.10(Predicted)
• Flash Point: 133.3oC
• PSA: 26.02000
• Density: 2.022g/cm3
• LogP: 3.37500
• Storage Temp.: Keep Cold

Purity/Quality:

99% ^*data from raw suppliers

3,5-Dibromoaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-Dibromoaniline

There total 26 articles about 3,5-Dibromoaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3,5-dibromonitrobenzene (6311-60-0) → 3,5-dibromoaniline (626-40-4)

Guidance literature:

With hydrogenchloride; tin; at 90 ℃; for 7h;

DOI:10.1002/chem.200400544

Reference yield: 81.0%

1,3,5-trisbromobenzene (626-39-1) → 3,5-dibromoaniline (626-40-4)

Guidance literature:

With bis(triphenylphosphine)nickel(II) chloride; lithium hexamethyldisilazane; In toluene; at 100 ℃; for 2h; Glovebox; Sealed tube;

DOI:10.1021/acs.organomet.8b00567

Reference yield: 56.0%

3,5-dibromophenylboronic acid (117695-55-3) → 3,5-dibromoaniline (626-40-4)

Guidance literature:

With O-(2,4-dinitrophenyl)hydroxylamine; In toluene; at 100 ℃; for 30h; Inert atmosphere;

DOI:10.1021/ja309637r

upstream raw materials:

3,5-dibromonitrobenzene

hydrogenchloride

N,N'-bis-(3,5-dibromo-phenyl)-hydrazine

sulfuric acid

Downstream raw materials:

N-(3,5-dibromophenyl)formamide

1,3,5-trisbromobenzene

1,3-dibromobenzene

1,3-dibromo-5-chlorobenzene

Refernces

• 1、 Shen, Zeyu,Hong, Lirui,Zheng, Baishu,Wang, Guanyu,Zhang, Beibei,Wang, Zhaoxu,Zhan, Feiyang,Shen, Shaohua,Yun, Ruirui. "Highly Efficient and Chemoselective Hydrogenation of Nitro Compounds into Amines by Nitrogen-Doped Porous Carbon-Supported Co/Ni Bimetallic Nanoparticles". supporting information. p. 16834 - 16839. Retrieved 2021/11/17.
• 2、 Navale, Tushar S.,Ivanov, Maxim V.,Hossain, Mohammad M.,Rathore, Rajendra. "FHBC, a Hexa-peri-hexabenzocoronene–Fluorene Hybrid: A Platform for Highly Soluble, Easily Functionalizable HBCs with an Expanded Graphitic Core". supporting information. p. 790 - 794. Retrieved 2017/12/26.