Estradiol 17-butyrate

Base Information

Chemical Name:Estradiol 17-butyrate
CAS No.:18069-79-9
Molecular Formula:C22H30 O3
Molecular Weight:342.478
Hs Code.:
European Community (EC) Number:241-977-5
UNII:340308DJ8M
DSSTox Substance ID:DTXSID90939375
Nikkaji Number:J260.861H
Wikidata:Q27256305
Mol file:18069-79-9.mol

Synonyms:estradiol 17-butyrate

Suppliers and Price of Estradiol 17-butyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Estradiol17-Butyrate
250mg
$ 1110.00

Total 12 raw suppliers

Chemical Property of Estradiol 17-butyrate

Chemical Property:

Boiling Point:474.3°Cat760mmHg
Flash Point:188°C
PSA：46.53000
Density:1.15g/cm³
LogP:4.96020
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Ethanol (Slightly)
XLogP3:5.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:342.21949481
Heavy Atom Count:25
Complexity:504

Purity/Quality:

99%, ^*data from raw suppliers

Estradiol17-Butyrate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC(=O)OC1CCC2C1(CCC3C2CCC4=C3C=CC(=C4)O)C
Isomeric SMILES:CCCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=C3C=CC(=C4)O)C
Uses An Estradiol (E888000) 17-monoester. Short-chain fatty acid esters have a higher binding potency to the estrogen receptor than long-chain fatty acid esters. ge form from which estradiol is released by enzymic hydrolysis. An Estradiol (E888000) 17-monoester. Short-chain fatty acid esters have a higher binding potency to the estrogen receptor than long-chain fatty acid esters. Estradiol fatty acyl esters act as a storage form from which estradiol is released by enzymic hydrolysis.

Technology Process of Estradiol 17-butyrate

There total 3 articles about Estradiol 17-butyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 63042-23-9
3.17β-dibutyryloxy-estratriene-(1.3.5(10))

: 18069-79-9
1,3,5(10)-Estratriene-3,17β-diol 17-propionate

Guidance literature:: With methanol; sodium carbonate; at 20 ℃;
DOI:10.1002/hlca.19370200137

Reference yield:

: 50-28-2
estradiol

: 107-92-6
butyric acid

: 18069-79-9
1,3,5(10)-Estratriene-3,17β-diol 17-propionate

Guidance literature:: DOI:10.1111/1467-954X.00223

Reference yield:

: 50-28-2
estradiol

: 18069-79-9
1,3,5(10)-Estratriene-3,17β-diol 17-propionate

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 115 °C

2: K₂CO₃; aqueous methanol / 20 °C

With pyridine; methanol; potassium carbonate;
DOI:10.1002/hlca.19370200137