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Product FOB Price Min.Order Supply Ability Supplier
Estradiol hot sales
Cas No: 50-28-2
No Data 1 Kilogram 1000 Kilogram/Month Shaanxi wuzhiyuan biotech co.,LTD Contact Supplier
Estradiol (E2)
Cas No: 50-28-2
USD $ 11.0-11.0 / Gram 5 Gram 500 Kilogram/Month Hebei Ruishun Trade Co.,Ltd Contact Supplier
Estradiol 50-28-2 98%MIN factory
Cas No: 50-28-2
USD $ 15.0-15.0 / Gram 1 Gram 10 Kilogram/Month Antimex Chemical Limied Contact Supplier
17β-estradiol Pharmaceutical Intermediate Estradiol Estrogen Steroids CAS 50-28-2
Cas No: 50-28-2
No Data 10 Gram 10000 Metric Ton/Month Hubei XinRunde Chemical Co., Ltd Contact Supplier
High quality lower price 99.5% pure API powder Estradiol/β-estradiol CAS:50-28-2 Standard of USP,EP ,manufacture of China
Cas No: 50-28-2
USD $ 10.0-10.0 / Gram 100 Gram 100 Kilogram/Year Hubei MQ FengDa Technology Co.,LTD Contact Supplier
Estradiol
Cas No: 50-28-2
No Data 100 Gram Metric Ton/Day Yicheng Goto Pharmaceuticals Co.,Ltd. Contact Supplier
Estradiol powder CAS 50-28-2
Cas No: 50-28-2
USD $ 100.0-200.0 / Kilogram 1 Kilogram 1000 Kilogram/Month Binbo Biological Co., Ltd Contact Supplier
Estradiol
Cas No: 50-28-2
USD $ 1.0-1.0 / Kilogram 1 Kilogram Metric Ton/Day JIANGSU GRAND XINYI PHARMACEUTICAL CO.,LTD Contact Supplier
High quality β-estradiol
Cas No: 50-28-2
USD $ 1.0-1.0 / Kilogram 10 Kilogram 50 Metric Ton/Day Hubei Jusheng Technology Co., Ltd., Contact Supplier
CAS:50-28-2 Estradiol
Cas No: 50-28-2
No Data 1 Kilogram 100 Kilogram/Month Kono Chem Co.,Ltd Contact Supplier

50-28-2 Usage

Biological Activity

Endogenous estrogen receptor (ER) agonist (K i values are 0.12 and 0.13 nM for ER α and ER β respectively). Also high affinity ligand at membrane estrogen GPR30 receptors.

Purification Methods

17-Estradiol (previously known as -estradiol) is purified by chromatography on SiO2 (toluene/EtOAc 4:1) and recrystallised from CHCl3/hexane or 80% EtOH. It is stable in air, is insoluble in H2O, and is precipitated by digitonin. The UV has max at 225 and 280 nm. The diacetate [3434-88-6] has m 97-98o and forms leaflets from aqueous EtOH. The 3-benzoate crystallises from aqueous MeOH withm 193o and [] D 25 +58o to 63o (c 1, dioxane). [Meischer & Scholz Helv Chim Acta 20 263, 1237 1937, Biochem J 32 1273 1938, Oppolzer & Roberts Helv Chim Acta 63 1703 1980, Inhoffen & Zühlsdorff Chem Ber 7 4 1914 1941, Beilstein 6 IV 6611.]

Adverse reactions

In high dosages, estradiol can inhibit the release of anterior pituitary prolactin, thus decreasing breast milk secretion. However, nausea, vomiting and endometrial hyperplasia-induced bleeding may occur. Patients with liver or kidney failure should use with caution.

Uses

Potent mammalian estrogenic hormone produced by the ovary.

Contact allergens

Natural estradiol, used in transdermal systems for hormonal substitution, can induce allergic contact dermatitis, with the risk of systemic contact dermatitis after oral reintroduction.

Chemical Properties

White Crystalline Powder

Contradictions

Do not use on breasts, vaginal area and vaginal mucosa.

Uses

Estradiol is the major estrogen secreted by the premenopausal ovary.

Definition

ChEBI: The 17beta-isomer of estradiol.

Indications and Usage

Estradiol is a white or milky white ordorless crystalline powder. It is soluble in dioxane and acetone, slightly soluble in ethanol, and insoluble in water.
Estradiol is the intermediate between estradiol valerate and estradiol benzoate, and it is a type of estrogen drug. It can be used to treat uterine functional bleeding, primary amenorrhea, menopausal syndrome, and prostate cancer. Estradiol can promote and adjust the normal growth of female sex organs and secondary sex characteristics, promote mammary duct maturation and growth, and aid in posseting. Estradiol can also be used in biochemical research.
InChI:InChI=1/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m0/s1

50-28-2 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Sigma (E8875)  β-Estradiol  ≥98% 50-28-2 E8875-100G 37,486.80CNY Detail
Sigma (E8875)  β-Estradiol  ≥98% 50-28-2 E8875-25G 17,760.60CNY Detail
Sigma (E8875)  β-Estradiol  ≥98% 50-28-2 E8875-5G 4,450.68CNY Detail
Sigma (E8875)  β-Estradiol  ≥98% 50-28-2 E8875-1G 1,281.15CNY Detail
Sigma (E8875)  β-Estradiol  ≥98% 50-28-2 E8875-250MG 600.21CNY Detail
Alfa Aesar (L03801)  beta-Estradiol, 99% (dry wt.), ca 3% water    50-28-2 25g 5984.0CNY Detail
Alfa Aesar (L03801)  beta-Estradiol, 99% (dry wt.), ca 3% water    50-28-2 5g 1492.0CNY Detail
Alfa Aesar (L03801)  beta-Estradiol, 99% (dry wt.), ca 3% water    50-28-2 1g 383.0CNY Detail
TCI America (E0025)  β-Estradiol  >97.0%(GC) 50-28-2 25g 2,480.00CNY Detail
TCI America (E0025)  β-Estradiol  >97.0%(GC) 50-28-2 5g 680.00CNY Detail
TCI America (E0025)  β-Estradiol  >97.0%(GC) 50-28-2 1g 223.00CNY Detail

50-28-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 17β-estradiol

1.2 Other means of identification

Product number -
Other names 17-Beta-Estradiol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Veterinary Drug: PRODUCTION_AID
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:50-28-2 SDS

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